Abstract

Effect of acute/subchronic samarium exposure on the concentration, motility, and morphology of sperm in male mice

Author(s): D.Y. Zhang, X.Y. Shen, X.L. Xu, Q. Ruan, SS. Hu, Y.Y. Chen and Z.M. Wang

Male ICR mice were orally administered samarium nitrate [Sm(NO3)3] to investigate its effects on sperm concentration and sperm quality. After acute exposure to ≥2880.00 mg/kg Sm(NO3)3 via intragastric gavage, sperm motility and acrosome integrity were decreased, and the sperm malformation percentage was increased (P 3)3 administered via drinking water for 90 days, relative gonad weight, sperm concentration, and sperm quality significantly decreased.

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