Abstract

Epidemiological investigation of community-acquired Staphylococcus aureus infection

The current study aimed to reveal the pathogenic and spreading mechanisms of community-acquired Staphylococcus aureus (CA-SA) by analyzing its prevalence, drug resistance, virulence, and pathogenic factors. Historical information regarding CA skin and soft tissue infections were collected and disease characteristics were analyzed. Isolated CA-SA strains were subjected to antibiotic sensitivity tests using the agar dilution method, Staphylococcus cassette chromosome mec (SCCmec) tests, multilocus sequence typing (MLST), and staphylococcal protein A (SPA) and toxin gene screening. A total of 55 skin and soft tissue infections were investigated, and 12 strains of SA bacteria were isolated, which were all CA methicillin-susceptible SA (CA-MSSA). The antibiotic sensitivity tests showed that CA-MSSA was susceptible to all antibacterials with the exception of high resistance to erythromycin, clindamycin, tetracycline, gentamicin, and levofloxacin (ranging from 8.3 to 50%).

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