Abstract

Estimates of genetic parameters and genotypic values prediction in maize landrace populations by REML/BLUP procedure

Author(s): D. Baretta, M. Nardino, I.R. Carvalho, A.J. de Pelegrin, M. Ferrari, V.J. Szareski, W.S. Barros, V.Q. de Souza, A.C. de Oliveira and L.C. da Maia

Lung cancer is the leading cause of cancer death in men and the second leading cause of cancer death in women worldwide. Fascin-1 and laminin-5 were associated with the invasiveness and prognoses of several cancers. The expression and the serum levels of fascin-1 and laminin-5 in patients with non-small cell lung cancer (NSCLC) were analyzed in this study. The expression of fascin-1 and laminin-5 were examined in 378 patients and their serum level was measured in 154 patients. The health of all patients was followed post-surgery. The expression of fascin-1 (P = 0.000) and lanminin-5 (P = 0.001) and the serum levels of fascin-1 (P = 0.015) and laminin-5 (P = 0.046) were related to the relapse of patients with NSCLC. Both serum levels and expression of fascin-1 and laminin-5 can be used to effectively evaluate the prognoses of patients with NSCLC.

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