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A.P.A.D. Gurgel

Publications of : A.P.A.D. Gurgel
Human Genetics   Research Article

Synergic effect of oral contraceptives, GSTP1 polymorphisms, and high-risk HPV infection in development of cervical lesions

Human papillomavirus (HPV) infection is considered a risk factor for cervical cancer. Even if the high-risk HPV (HR-HPV) infection is necessary, environmental co-factors and genetic susceptibility also play an important role in cervical cancer development. In this study, a possible association of rs1695 GSTP1 polymorphisms, HR-HPV infection, and oral contraceptive u.. Read More»

Genet. Mol. Res. 16(3): gmr16039742

DOI: 10.4238/gmr16039742

Human Genetics   Research Article

Prevalence of human papillomavirus (HPV), distribution of HPV types, and risk factors for infection in HPV-positive women

    M.V.C. Santos Filho, A.P.A.D. Gurgel, C.D.P. Lobo, A.C.F. Freitas, J.C. Silva-Neto and L.A.F. Silva

The aim of this study was to describe the prevalence of human papillomavirus (HPV), the distribution of different HPV types, and the putative risk factors for infection among HPV-positive women from the State of Alagoas, Northeast Brazil. We analyzed data from 515 patients attending public and private health centers. HPV DNA from cervical samples was extracted and H.. Read More»

Genet. Mol. Res. 15(2): gmr.15028315

DOI: 10.4238/gmr.15028315