A.V. Felipe
DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer
Purpose: Epigenetic changes can be detected in precancerous lesions, suggesting that may be involved in the early stages of carcinogenesis. The methylation of specifics genes has been correlated with the outcome of many different types of cancers. This study compared the levels of DNA methylation between normal and tumor tissues from patients with colorectal cancer .. Read More»
Genet. Mol. Res. 16(4): gmr16039816
DOI: 10.4238/gmr16039816
CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer
We investigated a possible association between alcoholism, cigarette smoking, obesity and CYP2E1 RsaI and 96-bp insertion genetic polymorphisms with risk for colorectal cancer (CRC). Patients with CRC (70 women and 61 men) were matched for gender and age to 206 healthy controls. The mean age of the two groups was 62 years. Meat intake, cigarette smoking and alcohol drinking were assessed using .. Read More»
Genet. Mol. Res. 11(3): 2012.September.3.2
DOI: 10.4238/2012.September.3.2
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