B. Zhu
Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer
Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function and protein expression. We examined the .. Read More»
Genet. Mol. Res. 16(3): gmr16038826
DOI: 10.4238/gmr16038826
MicroRNA-122 is involved in oxidative stress in isoniazid-induced liver injury in mice
Many studies have shown that the pathogenesis of liver injury includes oxidative stress. MicroRNA-122 may be a marker for the early diagnosis of drug-induced liver injury. However, the relationship between microRNA-122 and oxidative stress in anti-tuberculosis drug-induced liver injury remains unknown. We measured changes in tissue microRNA-122 levels and indices of oxidative stress during live.. Read More»
Genet. Mol. Res. 14(4): 2015.October.26.22
DOI: 10.4238/2015.October.26.22
Glutathione S-transferase polymorphisms in varicocele patients: a meta-analysis
The glutathione S-transferase (GST) family represents a major group of detoxification and antioxidant enzymes. Studies have shown that high oxidative stress levels are associated with varicocele. The objective of this study was to assess the relationship between GSTM1 and GSTT1 null polymorphisms and varicocele using a study group of 497 varicocele patients and 476 control subjects. A systemati.. Read More»
Genet. Mol. Res. 14(4): 2015.December.28.34
DOI: 10.4238/2015.December.28.34
Effects of high intensity exhaustive exercise on SOD, MDA, and NO levels in rats with knee osteoarthritis
The aim of this study was to investigate the impact of high intensity exhaustive exercise on nitric oxide (NO), malondialdehyde (MDA), and superoxide dismutase (SOD) expression in rats with knee osteoarthritis. Sprague Dawley rats were randomly divided into control (N = 5) and model (N = 35) groups; the model group was further divided into quiet (N = 5), low- (N = 1.. Read More»
Genet. Mol. Res. 14(4): 2015.October.16.3
DOI: 10.4238/2015.October.16.3
Association between the PADI4 -94G/A polymorphism and rheumatoid arthritis: a meta-analysis in the Chinese population
Although a number of studies have been conducted on the association between the peptidylarginine deiminase (PADI4) -94G/A polymorphism and rheumatoid arthritis (RA) in the Chinese population, the association remains elusive and controversial. To clarify the impact of the PADI4 -94G/A polymorphism on the risk of RA, a meta-analysis was performed in the Chinese population. Related studies were id.. Read More»
Genet. Mol. Res. 15(1): gmr.15017391
DOI: 10.4238/gmr.15017391
Identification of CD14 transcript in blood polymorphonuclear neutrophil leukocytes and functional variation in Holsteins
Polymorphonuclear neutrophil (PMN) leukocytes are primary phagocytic cells of the bovine mammary gland and a first line of defense against invading pathogens during bovine mastitis infection. Cluster of differentiation 14 (CD14) is mainly expressed in macrophages and neutrophils and acts as a co-receptor that binds bacterial lipopolysaccharide (LPS) and recruits PMN.. Read More»
Genet. Mol. Res. 15(2): gmr.15027932
DOI: 10.4238/gmr.15027932
Isolation and identification of new pollen-specific SFB genes in Japanese apricot (Prunus mume)
SFB, a candidate gene for the pollen S gene, has been identified in several species of Prunus (Rosaceae). We isolated 5 new SFB alleles from 6 Japanese apricot (Prunus mume) lines using a specific Prunus SFB primer pair (SFB-C1F and Pm-Vb), which was designed from conserved regions of Prunus SFB. The nucleotide sequences of these SFB genes were submitted to the GenBank database. The 5 new SFB a.. Read More»
Genet. Mol. Res. 12(3): 2013.September.3.5
DOI: 10.4238/2013.September.3.5
Bioinformatic analysis of the nucleotide binding site-encoding disease-resistance genes in foxtail millet (Setaria italica (L.) Beauv.)
The nucleotide-binding site (NBS) disease-resistance genes are the largest category of plant disease-resistance gene analogs. The complete set of disease-resistant candidate genes, which encode the NBS sequence, was filtered in the genomes of two varieties of foxtail millet (Yugu1 and ‘Zhang gu’). This study investigated a number of characteristics of th.. Read More»
Genet. Mol. Res. 13(3): 2014.August.28.5
DOI: 10.4238/2014.August.28.5
Protective effect and mechanism of probucol in the treatment of spinal cord injury
To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally injected into the treatment group rats for .. Read More»
Genet. Mol. Res. 14(3): 2015.July.17.11
DOI: 10.4238/2015.July.17.11
Effect of high-intensity exercise on interleukin-15 expression in rabbit synovia
The objective of this study was to examine the effect of high-intensity exercise on interleukin-15 (IL-15) expression in rabbit synovia. We utilized 24 New Zealand white rabbits, which were randomly divided equally into high-intensity exercise and control groups. The former were forced to run for 60 min/day over 4 weeks at the speed of 30 m/min. The histological changes of cartilage and knee jo.. Read More»
Genet. Mol. Res. 14(4): 2015.October.29.5
DOI: 10.4238/2015.October.29.5
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