Chol Kim
Identification of Klf6-Related Super Enhancer in Human Hepatoma (HepG2) Cells by CRISPR Technique
The Klf6 gene is a tumor suppressor gene belonging to the family of the Klf gene and closely associated with tumor formation. Recently, super enhancers(SEs) have been shown to play a particularly important role in regulating cell identity and are attempting to evaluate the in vivo function of SEs. But direct functional evidence of SE associated with Klf6 is lacking... Read More»
Genet. Mol. Res. 16(4): gmr16039841
DOI: 10.4238/gmr16039841
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells
Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is considered as one of tumor suppressor gene.. Read More»
Genet. Mol. Res. 17(1): gmr16039888
DOI: 10.4238/gmr16039888
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