Childhood obesity is a serious public health concern condition, as excess body fat can negatively affect a child's health. Obestatin is a hormone that regulates body weight by suppressing appetite and reducing food intake; fasting obestatin level is negatively correlated with basal insulin level. This study aims to investigate the role of obestatin in insulin resist.. Read More»
Genet. Mol. Res. 16(2): gmr16029210
DOI: 10.4238/gmr16029210
We conducted a hospital-based case-control study to evaluate the association between polymorphisms in excision repair cross-complementing group 1-xeroderma pigmentosum group F (ERCC1-XPF) variants and the risk of colorectal cancer in a Chinese population. Genotyping of the ERCC1 rs2298881 and rs11615 and XPF rs2276466 polymorphisms were detected by polymerase chain reaction-restriction fragment le.. Read More»
Genet. Mol. Res. 14(1): 2015.January.30.13
DOI: 10.4238/2015.January.30.13
We aimed to evaluate the effect of melatonin on myocardial cell oncosis in the myocardial ischemia/reperfusion injury rat, and the role of the mitochondrial permeability transition pore (MPTP) therein. Sprague Dawley rats (N = 60) were randomly divided into five groups of 12 rats each: control, ischemia/reperfusion (I/R), melatonin treatment (MT), melatonin treatment + atractyloside (MT+ATR), a.. Read More»
Genet. Mol. Res. 14(3): 2015.July.3.24
DOI: 10.4238/2015.July.3.24
Twenty-five populations of Oryza rufipogon from China and 144 cultivars of Oryza sativa were selected for this study. Based on the DNA fragment of Ehd1-4 and subspecies-specific sequence-tagged site markers in different chromosomes, intraspecific differentiation in O. rufipogon from China was analyzed. The introgression from O. sativa to O. rufipogon was also analyz.. Read More»
Genet. Mol. Res. 12(4): 2013.December.2.8
DOI: 10.4238/2013.December.2.8
Recent data have indicated that inflammation may have an important correlation with obstructive sleep apnea (OSA). Studies have indicated a relationship between OSA and TNF-α gene polymorphisms. Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs. However, ZFP36 gene polymorphisms have not been investigated in OSA. Therefore, we conducted the present case-control study to assess wh.. Read More»
Genet. Mol. Res. 14(2): 2015.June.18.17
DOI: 10.4238/2015.June.18.17
In regard to the affiliation mistake that was made during our correspondence in our manuscript, we write this letter in order to correct it as per my PhD requirements and this is the Final decision as I have no other option. The correction is only in the affiliation and should be: T.N. Mahmoud1,2, P.F. Lin1, F.L. Chen1, J.H. Zhou1, X.G. Wang1, N. Wang1, X. Li1 and Y.P. Jin1. 1Key Laboratory of .. Read More»
Genet. Mol. Res. 15(1): gmr.150156091
DOI: 10.4238/gmr.150156091
Epigenetic silencing of the GSTP1 gene by promoter methylation has been associated with increased risk and shortened survival in patients with hepatocellular carcinoma (HCC). We therefore conducted a meta-analysis to obtain a more precise estimate of this association. By searching the Cochrane Library, CBM, EMBASE, PubMed, and the Web of Science, we tabulated and analyzed parameters from each s.. Read More»
Genet. Mol. Res. 14(2): 2015.June.18.19
DOI: 10.4238/2015.June.18.19
It is very important to investigate the reasons for the large individual differences in individual performance of food acceptance when using formulated diets for the successful culture of larvae and juveniles of the Chinese sturgeon Acipenser sinensis. Genetic differences of the mitochondrial control region were investigated by direct sequencing in two groups of Chinese sturgeon, which were apt.. Read More»
Genet. Mol. Res. 12(4): 2013.October.15.4
DOI: 10.4238/2013.October.15.4
The developmental dynamics of DNA methylation events have been well studied. Active demethylation of the paternal genome occurs in the zygote, passive demethylation occurs during cleavage stages, and de novo methylation occurs by the blastocyst stage. It is believed that the paternal genome has lower levels of methylation during early development than the maternal genome. However, in this study.. Read More»
Genet. Mol. Res. 13(4):
Dahurian larch (Larix gmelinii), a deciduous conifer, is the northernmost tree, native to eastern Siberia and nearby regions of China. We used growth traits and molecular markers to assess genetic variation in different L. gmelinii growing regions; 105 individual samples were collected from seven regions of the Qingshan Forestry Centre, Heilongjiang Province, China. The greatest genetic regional v.. Read More»
Genet. Mol. Res. 12(1): 2013.January.24.12
DOI: 10.4238/2013.January.24.12
Genetics and Molecular Research received 56184 citations as per google scholar report