G. Liu
Effect of 1,25(OH)2D3 on the proliferation of human mesangial cells and their expression of Ki67
Previous studies have found that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3 or VD3] exerts many biological effects, including the inhibition of cell proliferation and induction of apoptosis, but its mechanism of action remains unclear. The goal of our investigation was to explore the effects of 1,25(OH)2D3 on the proliferation of cultured human mesangial cells and their .. Read More»
Genet. Mol. Res. 16(2): gmr16029191
DOI: 10.4238/gmr16029191
Screening and identification of microsatellite markers associated with cold tolerance in Nile tilapia Oreochromis niloticus
Tilapia is an important fish cultured in tropical and subtropical areas. Cold sensitivity limits the expansion of tilapia culture into colder regions of the world, and mass mortalities of cultured tilapia have been reported due to severe cold currents in winter. Since the late 1990s, several strains of Nile tilapia have been domesticated to improve the ability to adapt to low temperatures. Prev.. Read More»
Genet. Mol. Res. 14(3): 2015.August.28.16
DOI: 10.4238/2015.August.28.16
Immunohistochemical detection and clinicopathological significance of JARID1B/ KDM5B and P16 expression in invasive ductal carcinoma of the breast
The aims of this study were to investigate the expression of the H3K4 demethylase, jumonji AT-rich interactive domain 1B (JARID1B/KDM5B) and of p16 (multiple tumor suppressor gene MTS1) in breast cancer tissue and determine its clinicopathological significance. JARID1B/KDM5B and P16 protein expression in 176 resected breast cancer specimens and adjacent normal breast tissue was detected by the .. Read More»
Genet. Mol. Res. 14(2): 2015.May.22.11
DOI: 10.4238/2015.May.22.11
Correlation of forkhead box transcription factor O1 and myosin heavy chain isoforms in porcine skeletal muscle
We examined the expression of myosin heavy chain (MyHC) isoforms and forkhead box transcription factor O1 (FoxO1) in porcine soleus and extensor digitorum longus (EDL) muscles to clarify the correlation of FoxO1 and the relative abundance of transcripts of MyHC isoforms. Soleus muscle was found to be redder than EDL muscles in pigs, and immunohistochemical fast MyHC staining showed more oxidati.. Read More»
Genet. Mol. Res. 13(4): 2014.December.4.18
DOI: 10.4238/2014.December.4.18
Correlation between Y chromosome microdeletion and male infertility
Dyszoospermia due to genetic factors is the leading cause of male infertility. To explore the correlation between azoospermia factor (AZF) microdeletion of the Y chromosome and male infertility, we evaluated AZF microdeletion on the long arm of the Y chromosome in 166 infertile males and 50 fertile males using multiplex polymerase chain reactions amplification and g.. Read More»
Genet. Mol. Res. 15(2): gmr.15028426
DOI: 10.4238/gmr.15028426
Implications of microRNA-197 downregulated expression in esophageal cancer with poor prognosis
The aim of this study was to investigate the significance of the microRNA miR-197 expression level in relation to clinicopathological factors and prognoses of esophageal cancer (EC). MicroRNA was extracted using the Taqman® MicroRNA Assay from 46 EC patients at the same tumor node metastasis (TNM) stage, but with different prognoses, who underwent surgery. Parac.. Read More»
Genet. Mol. Res. 13(3): 2014.July.25.12
DOI: 10.4238/2014.July.25.12
Clinical application of carbon nanoparticle lymph node tracer in the VI region lymph node dissection of differentiated thyroid cancer
The application and clinical significance of carbon nanoparticle lymph tracer in the VI region (central region) lymph node dissection of differentiated thyroid cancer was investigated. Eighty patients with differentiated thyroid cancer were equally divided into the carbon nanoparticle-marked group (ipsilateral thyroid injection) and the control group (no injection)... Read More»
Genet. Mol. Res. 13(2): http://dx.doi.org/2014.April.30.4
DOI: http://dx.doi.org/10.4238/2014.April.30.4
Detection of serum anti-melanocyte antibodies and identification of related antigens in patients with vitiligo
We detected autoantibodies against melanocytes in serum samples obtained from 50 patients, including 4 with HBV, with vitiligo and identified the associated membrane antigens. Heat shock protein 70 (HSP70) and anti-tyrosinase-related protein 1 (TRP-1) antibody levels were analyzed. The associated antigens in normal human melanocyte were identified by immunofluoresce.. Read More»
Genet. Mol. Res. 14(4): 2015.December.7.19
DOI: 10.4238/2015.December.7.19
Effect of TIEG1 on apoptosis and expression of Bcl-2/Bax and Pten in leukemic cell lines
We examined the effect of transforming growth factor-b inducible early gene-1 (TIEG1) on the apoptosis of leukemic cell lines and expression of B-cell lymphoma 2 (Bcl-2) and phosphatase and tensin homolog (Pten). Four leukemic cell lines (HL-60, U937, Raji, and K562) were treated with 0, 1, 5, 10, and 20 ng/mL TIEG1, respectively. The cell growth inhibitory ratio was assessed using t.. Read More»
Genet. Mol. Res. 14(1): 2015.March.20.6
DOI: 10.4238/2015.March.20.6
Expression and serological diagnosis of Mycobacterium tuberculosis CFP-10 and Rv2626c proteins
We constructed a Mycobacterium tuberculosis vector expressing CFP-10 and Rv2626c to examine the expression of these proteins in Escherichia coli as well as their immunoreactivity. The CFP-10 and Rv2626c genes were amplified from tuberculosis H37Rv genomic DNA using polymerase chain reaction. They were ligated into the expression vector PET30a and e.. Read More»
Genet. Mol. Res. 13(3): 2014.September.12.5
DOI: 10.4238/2014.September.12.5
Impact Factor an Index
Google scholar citation report
Citations : 56184
Genetics and Molecular Research received 56184 citations as per google scholar report
