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Ghaneema Enad Al-shammari

Publications of : Ghaneema Enad Al-shammari
Human Genetics   Research Article

Detection of HER2 gene amplification in formalin-fixed and paraffin-embedded breast cancer tissues by quantitative real time polymerase chain reaction in ER and PR-positive HER2 immunohistochemistry 0 or ≥ 2+ breast cancer

Amplification of the human epidermal growth factor receptor 2 (HER2) genes and overexpression of its gene product, the HER2 protein was found in 20% of breast cancers. Genetic instability and hence aberrant HER2 amplification may be associated with breast cancer progression. HER2 status determination plays an important role in selecting the best treatment opt.. Read More»

Genet. Mol. Res. 23(4):