H. Zhang
Association of three common single nucleotide polymorphisms of SLC7A7 with the development of glioma in a Chinese population
Gliomas are brain tumors that can be seriously damaging to human health. The SLC7 family is involved in amino acid or peptide transportation. The relationship between SLC7A7 polymorphisms and the development of glioma has been reported previously by a few studies. Therefore, we performed a hospital based case-control study to investigate the association of three com.. Read More»
Genet. Mol. Res. 16(2): gmr16029026
DOI: 10.4238/gmr16029026
Screening and analyzing genes associated with Amur tiger placental development
The Amur tiger is a unique endangered species in the world, and thus, protection of its genetic resources is extremely important. In this study, an Amur tiger placenta cDNA library was constructed using the SMART cDNA Library Construction kit. A total of 508 colonies were sequenced, in which 205 (76%) genes were annotated and mapped to 74 KEGG pathways, including 29.. Read More»
Genet. Mol. Res. 13(3): 2014.September.26.25
DOI: 10.4238/2014.September.26.25
Differential gene expression of epigenetic modifying enzymes between Tibet pig and Yorkshire in high and low altitudes
Epigenetic modifying enzymes play important roles in the adaptation to hypoxia, although no studies have examined their expression levels in Tibet pigs. The lung is an important functional organ in hypoxia adaptation. In this study, we examined the mRNA expression level of 5 enzymes in the lung of Tibet pigs using real-time polymerase chain reaction to determine the epigenetic performance of hy.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.13.6
DOI: http://dx.doi.org/10.4238/2015.April.13.6
Genome-wide identification, phylogenetic relationships, and expression analysis of the carotenoid cleavage oxygenase gene family in pepper
Carotenoid cleavage oxygenases (CCOs) are a family of dioxygenases, which specifically catalyze the cleavage of conjugated double bonds in carotenoids and apocarotenoids in plants. In this study, genome-wide analysis of CCO genes in pepper plants was performed using bioinformatic methods. At least 11 members of the CCO gene family were identified in the pepper genom.. Read More»
Genet. Mol. Res. 15(4): gmr.15048695
DOI: 10.4238/gmr.15048695
Gene expression patterns of invertase gene families and modulation of the inhibitor gene in tomato sucrose metabolism
Patterns of gene expression in the different types of sucrose metabolism in the tomato are highly variable and heritable. This genetic variation causes considerable functional differences. We examined the patterns of expression of invertase (Inv) gene families and an invertase inhibitor (INH) gene involved in elongating roots, hypocotyls, and fruit of the tomato (Lycopersicon esculentum cv. Mic.. Read More»
Genet. Mol. Res. 12(3): 2013.January.24.1
DOI: 10.4238/2013.January.24.1
Effect of melatonin on oncosis of myocardial cells in the myocardial ischemia/reperfusion injury rat and the role of the mitochondrial permeability transition pore
We aimed to evaluate the effect of melatonin on myocardial cell oncosis in the myocardial ischemia/reperfusion injury rat, and the role of the mitochondrial permeability transition pore (MPTP) therein. Sprague Dawley rats (N = 60) were randomly divided into five groups of 12 rats each: control, ischemia/reperfusion (I/R), melatonin treatment (MT), melatonin treatment + atractyloside (MT+ATR), a.. Read More»
Genet. Mol. Res. 14(3): 2015.July.3.24
DOI: 10.4238/2015.July.3.24
Whole-genome duplications contributed to the expansion of cytochrome b5 genes in Paramecium tetraurelia
Cytochrome b5 (cyt b5) genes encode ubiquitous electron transport hemoproteins found in animals, plants, fungi, and purple bacteria. However, little is known about their evolutionary history in genomes so far. Here, we conducted an extensive genome-wide survey of cyt b5 genes in 20 representative model species and identified 310 of these genes. Both the absolute number and relative proportion o.. Read More»
Genet. Mol. Res. 12(2): 2013.January.9.1
DOI: 10.4238/2013.January.9.1
Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis
Celiac disease (CD) is a common autoimmune disorder characterized by heightened immunological response to ingested gluten. Certain gene polymorphisms of IL2/IL21 (rs6822844 and rs6840978) and SH2B3 (rs3184504) may influence susceptibility to CD, although the effects remain unclear. We performed a meta-analysis of the associations between rs6822844, rs6840978, and rs3184504 polymorphisms and CD .. Read More»
Genet. Mol. Res. 14(4): 2015.October.26.19
DOI: 10.4238/2015.October.26.19
Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea
Recent data have indicated that inflammation may have an important correlation with obstructive sleep apnea (OSA). Studies have indicated a relationship between OSA and TNF-α gene polymorphisms. Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs. However, ZFP36 gene polymorphisms have not been investigated in OSA. Therefore, we conducted the present case-control study to assess wh.. Read More»
Genet. Mol. Res. 14(2): 2015.June.18.17
DOI: 10.4238/2015.June.18.17
Drought-tolerant rice germplasm developed from an Oryza officinalis transformation-competent artificial chromosome clone
Oryza officinalis has proven to be a natural gene reservoir for the improvement of domesticated rice as it carries many desirable traits; however, the transfer of elite genes to cultivated rice by conventional hybridization has been a challenge for rice breeders. In this study, the conserved sequence of plant stress-related NAC transcription factors was selected as a probe to screen the O. offi.. Read More»
Genet. Mol. Res. 14(4): 2015.October.28.29
DOI: 10.4238/2015.October.28.29
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