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I.R. da Costa

Publications of : I.R. da Costa
Human Genetics   Research Article

Atherosclerosis: analysis of the eNOS (T786C) gene polymorphism

The coronary arteriosclerotic disease is the most common cardiovascular disease. Atherosclerosis affects large- and medium-sized arteries leading to severe thrombosis or artery stenosis that could evolve to myocardial infarction, ischemic stroke, ischemic injury of kidneys and intestines, and several other life-threatening clinical manifestations. Nitric oxide has b.. Read More»

Genet. Mol. Res. 16(3): gmr16039708

DOI: 10.4238/gmr16039708

Human Genetics   Research Article

Pterygium in patients from Goi�¢nia, Goi�¡s, Brazi

    G.M. dos Reis, A. de P.R. Júnior, K.S.F. e Silva, D.A. Rodrigues,M.C.S. Gomes, J.V.M. Martins, I.R. da Costa, G.A. Freitas andK.K.O. Moura

Pterygium is an inflammatory and degenerative ocular surface disease in which the conjunctiva on the cornea grows to form a fibrous tissue in the shape of a triangle. The disorder may be characterized by cell proliferation, inflammatory processes, fibrosis, angiogenesis, and destruction of the extracellular matrix. The anomaly is considered a degenerative eye disease and is erroneously confused.. Read More»

Genet. Mol. Res. 14(2): 2015.June.9.4

DOI: 10.4238/2015.June.9.4

Human Genetics   Research Article

Analysis of the GSTM1-null polymorphism in patients with pterygium from Goi�¢nia, Goi�¡s Brazil

    A. de P.R. Júnior, G.M. dos Reis, K.S.F. e Silva, D.A. Rodrigues, M.C.S. Gomes, J.V.M. Martins, I.R. da Costa, G.A. Freitas and K.K.V.O. Moura

The first reports about pterygium date back to Hippocrates, and this disease still threatens vision health around the world. Pterygium is a formation of fibrous tissue consisting of highly vascularized epithelial and subepithelial tissue that grows excessively and with an abnormal shape on the cornea. Many physical and biological factors are associated with the pathogenesis of pterygium, includ.. Read More»

Genet. Mol. Res. 14(2): 2015.June.9.3

DOI: 10.4238/2015.June.9.3

Human Genetics   Research Article

Association of CYP1A1 (cytochrome P450) MspI polymorphism in women with endometriosis

    A.M. Barbosa, S.R. de Souza,, A.B. Frare, R.C. Costa e Silva, I.R. da Costa, K.S. Freitas e Silva, C.L. Ribeiro Júnior, B.M. Bordin and K.K.V.O. Moura

Endometriosis is a disease that affects 10 to 15% of the women of reproductive age. It is characterized by the presence of endometrial-like tissues outside of the uterus. Some definitions claim that the functional ectopic tissue is sensitive to the action of hormones. Severity of endometriosis is defined according to a system proposed by the American Society for Reproductive Medicine, which is .. Read More»

Genet. Mol. Res. 15(3): gmr.15038389

DOI: 10.4238/gmr.15038389

Human Genetics   Research Article

Scientometric analysis: Five years of genetic polymorphisms

Scientometrics is a quantitative evaluation of scientific and technological activities. The main objective is to point the number of methodologies used in scientific studies or even the structure of several research centers. This type of metric study belongs to the area of sociology of scientific knowledge. It covers quantitative analyzes of scientific activities th.. Read More»

Genet. Mol. Res. 17(2): gmr16039913

DOI: 10.4238/gmr16039913