J. Li

Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases

• Z.-Z. Liang
• J. Li
• S.-G. Huang

The objective of this study was to observe the distribution of macrophages (MPs) expressing transforming growth factor beta-1 (TGF-β1) in tissue samples from patients with different human chronic periapical diseases. In this study, samples were collected from 75 volunteers, who were divided into three groups according to classified standards, namely, healthy co.. Read More»

Genet. Mol. Res. 16(1): gmr16019329

DOI: 10.4238/gmr16019329

Key pathways involved in prostate cancer based on gene set enrichment analysis and meta analysis

Q.Y. Ning, J.Z. Wu, N. Zang, J. Liang, Y.L. Hu and Z.N. Mo

Prostate cancer is one of the most common male malignant neoplasms; however, its causes are not completely understood. A few recent studies have used gene expression profiling of prostate cancer to identify differentially expressed genes and possible relevant pathways. However, few studies have examined the genetic mechanics of prostate cancer at the pathway level t.. Read More»

Genet. Mol. Res. 10(4): 2011.December.14.10

DOI: 10.4238/2011.December.14.10

Genome-wide identification, phylogenetic relationships, and expression analysis of the carotenoid cleavage oxygenase gene family in pepper

X.H. Zhang, H.Q. Liu, Q.W. Guo, C.F. Zheng, C.S. Li, X.M. Xiang, D.F. Zhao, J. Liu, J. Luo, D.K. Zhao, J.Q. Zheng and H.J. Wan

Carotenoid cleavage oxygenases (CCOs) are a family of dioxygenases, which specifically catalyze the cleavage of conjugated double bonds in carotenoids and apocarotenoids in plants. In this study, genome-wide analysis of CCO genes in pepper plants was performed using bioinformatic methods. At least 11 members of the CCO gene family were identified in the pepper genom.. Read More»

Genet. Mol. Res. 15(4): gmr.15048695

DOI: 10.4238/gmr.15048695

Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury

L.Y. Bi,D.A. Zhao,D.S. Yang,J.G. Guo,B. Liang,R.X. Zhang,J.L. Zhao,H.T. Bai and S.J. Li

To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 μg·kg-1·day-1) for 5 days.. Read More»

Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.27.25

DOI: http://dx.doi.org/10.4238/2015.April.27.25

De novo transcriptome analysis of tobacco seedlings and identification of the early response gene network under low-potassium stress

L.Q. Li, J. Li, Y. Chen, Y.F. Lu and L.M. Lu

Tobacco is an economically important crop, and its potassium content can greatly affect the quality of tobacco leaves. However, the molecular mechanism involved in potassium starvation in tobacco has not been elucidated to date. In this study, Illumina (Solexa) sequencing technology was used to analyze the transcriptome of tobacco seedlings under low-potassium stress for 6, 12, and 24 h. After .. Read More»

Genet. Mol. Res. 15(3): gmr.15038599

DOI: 10.4238/gmr.15038599

Multifocal central nervous system hemangioblastoma: a case report and review of the literature

L.Z. Chu, Z.Z. Guan, J. Liu, H. Yang, X.L. Qi, M.G. Dong, Y.M. Chen, Y.N. Xiang and Y. Li

An effective therapy for multifocal central nervous system hemangioblastoma (CNS HB) is needed. Here, we report a case of multifocal CNS HB. A 43-year-old man was diagnosed with CNS HB by enhanced computed tomography and magnetic resonance imaging. Six solid tumors and one cystic nodule were detected in his cerebellum. The patient underwent three surgeries followed .. Read More»

Genet. Mol. Res. 13(3): 2014.September.29.3

DOI: 10.4238/2014.September.29.3

Cloning and expression analysis of PpSUT2 encoding a sucrose transporter in pear

J. Tang, J. Lin, B.L. Zhang, Z.H. Wang, X.G. Li and Y.H. Chang

A 1794-bp cDNA fragment was amplified from mRNA isolated from pear (Pyrus pyrifolia NaKai. Cuiguan) leaves by using primers based on the sequences generated during the analysis of the pear transcriptome. The 597-amino acid sequence encoded by the cDNA was compared with the sequences in GenBank, and it was found to be similar to that of members of the sucrose-proton co-transporter family. The hy.. Read More»

Genet. Mol. Res. 13(4):

Polymorphic microsatellite loci developed from the Hong Kong oyster (Crassostrea hongkongensis)

H.T. Ma, S. Xiao, Y. Zhang, X.M. Li, J. Li and Z.N. Yu

Forty polymorphic microsatellite loci were developed from Crassostrea hongkongensis using an enriched partial genomic library with magnetic beads. The polymorphism of these loci was assessed in 30 individuals from a wild population. The allele number of the polymorphic markers ranged from 2 to 13, with an average of 5.8 per locus. The polymorphism information conten.. Read More»

Genet. Mol. Res. 15(4): gmr.15048676

DOI: 10.4238/gmr.15048676

Identifying differentially expressed genes and pathways in two types of non-small cell lung cancer: adenocarcinoma and squamous cell carcinoma

J. Liu, X.Y. Yang and W.J. Shi

Non-small cell lung carcinoma, NSCLC, accounts for 80-85% of lung cancers. NSCLC can be mainly divided into two types: adenocarcinoma (ADC) and squamous cell carcinoma (SCC). The purpose of our study was to identify and differentiate the pathogenesis of ADC and SCC at the molecular level. The gene expression profiles of ADC and SCC were downloaded from Gene Expressi.. Read More»

Genet. Mol. Res. 13(1): 2014.January.8.8

DOI: 10.4238/2014.January.8.8

Whole-transcriptome sequencing of Pinellia ternata using the Illumina platform

X. Huang, Y. Jing, D.J. Liu, B.Y. Yang, H. Chen and M. Li

Pinelliae rhizoma is the dried tuber of Pinellia ternata (Thunb.) Breit., and has been used for thousands of years as a traditional Chinese medicine. However, its genomic background is little known. With the development of high-throughput genomic sequencing, it is now easy and cheap to obtain genomic information. In this study, 193,032,910 high-quality clean reads w.. Read More»

Genet. Mol. Res. 15(2): gmr.15028062

DOI: 10.4238/gmr.15028062