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L. Kang

Publications of : L. Kang
Animal Genetics   Research Article

Differential gene expression in the peripheral blood of Chinese Sanhe cattle exposed to severe cold stress

Livestock is an important food resource for the inhabitants of cold regions, such as northern Asia and alpine regions, where agriculture is limited. In these regions, cold stress largely affects livestock production, thereby reducing the productivity and survival of animals. Despite the importance of breeding cold-tolerant animals, few studies have investigated the .. Read More»

Genet. Mol. Res. 16(2): gmr16029593

DOI: 10.4238/gmr16029593

Medical Genetics   Research Article

SLC2A9 and ZNF518B polymorphisms correlate with gout-related metabolic indices in Chinese Tibetan populations

    X.Y. Zhang, T.T. Geng, L.J. Liu, D.Y. Yuan, T. Feng, L.L. Kang, T.B. Jin and C. Chen

Current evidence suggests that heredity and metabolic syndrome contribute to gout progression. SLC2A9 and ZNF518B may play a role in gout progression in different populations, but no studies have focused on the Tibetan Chinese population. In this study, wedetermined whether variations in these 2 genes were correlated with gout-related indices in Chinese-Tibetan gout patients. We detected 6 sing.. Read More»

Genet. Mol. Res. 14(3): 2015.August.19.26

DOI: 10.4238/2015.August.19.26

Human Genetics   Research Article

No difference of complete or incomplete left-sided malignant colonic obstruction on both short- and long-term outcomes

    Z.-H. Liu, C. Li, N.-Q. Huang*, M.-J. Huang, H. Peng, L. Kang

The impact of complete and incomplete colonic obstruction on the short- and long-term outcomes of malignant colorectal cancer has not yet been elucidated. The aim of this study was to investigate whether there was a difference in the impacts of the 2 types of obstruction on the short- and long-term outcomes of colorectal resection. This study included 224 colorectal.. Read More»

Genet. Mol. Res. 13(3): 2014.September.29.10

DOI: 10.4238/2014.September.29.10

Human Genetics   Research Article

Genetic variation in WDR1 is associated with gout risk and gout-related metabolic indices in the Han Chinese population

    L.J. Liu, X.Y. Zhang, N. He K Liu, X.G. Shi, T. Feng, T.T. Geng, D.Y. Yuan, L.L. Kangand T.B. Jin

Gout is the most common form of inflammatory arthritis affecting men, and current evidence suggests that genetic factors contribute to its progression. As a previous study identified that WD40 repeat protein 1 (WDR1) is associated with gout in populations of European descent, we sought to investigate its relationship with this disease in the Han Chinese population. .. Read More»

Genet. Mol. Res. 15(2): gmr.15027381

DOI: 10.4238/gmr.15027381

Human Genetics   Research Article

PDK2 and ABCG2 genes polymorphisms are correlated with blood glucose levels and uric acid in Tibetan gout patients

    Y.C. Ren1,2*, T.B. Jin1,2,4,5*, X.D. Sun6, T.T. Geng2,3*, M.X. Zhang1,2, L. Wang4,5,T. Feng2, L.L. Kang4,5 and C. Chen1,2

Previous studies have shown that the PDK2 and ABCG2 genes play important roles in many aspects of gout development in European populations. However, a detailed genotype-phenotype analysis was not performed. The aim of the present study was to investigate the potential association between variants in these two genes and metabolism-related quantitative phenotypes relevant to gout in a Chinese Tib.. Read More»

Genet. Mol. Res. 15(1): gmr.15017447

DOI: 10.4238/gmr.15017447

Human Genetics   Research Article

Genetic polymorphisms in very important pharmacogenomic (VIP) variants in the Tibetan population

    T.B. Jin, X.J. Xun, X.G. Shi, D.Y. Yuan, T. Feng, T.T. Geng and L.L. Kang

Genetic polymorphisms of very important pharmacogenomic (VIP) variants are important for personalized medicine. However, these have not been extensively studied in the Tibetan population. In this study, 82 VIP variants were detected in the Tibetan and Han (HAN) populations from northwestern China. Subsequently, we compared the differences between the Tibetan populat.. Read More»

Genet. Mol. Res. 14(4): 2015.October.16.17

DOI: 10.4238/2015.October.16.17

Medical Genetics   Research Article

Bibliometric network analysis of glaucoma

    L.-Y. Dong, M. Yin and X.-L. Kang

Elevated intraocular pressure is recognized as the principal risk factor for development of optic nerve head (ONH) injury. Lamina cribrosa (LC) cells and astrocytes are two types of cells in the ONH. We attempted to identify more target genes and predict their underlying molecular mechanisms. In this study, we performed meta-analysis of the data from two microarray sets containing samples from .. Read More»

Genet. Mol. Res. 13(2): http://dx.doi.org/2014.May.9.1

DOI: http://dx.doi.org/10.4238/2014.May.9.1