L. Li
The effect of acetate Ringer's solution on inflammatory factors and NF-�ºB signal pathway in the liver of hemorrhagic shock rats
Purpose: To investigate the effect of resuscitation with acetated Ringer's solution during hemorrhagic shock (HS) on inflammatory factors and nuclear factor κB (NF-κB) signaling pathway in liver tissue. Methods: In this study, a rat HS model was established. HS rats received acetated Ringer's solution, lactated Ringer's solution and saline for fluid resuscitation. Inflammatory facto.. Read More»
Genet. Mol. Res. 17(2): gmr16039906
DOI: 10.4238/gmr16039906
Polymorphisms in interleukin-6 and interleukin-10 may be associated with risk of preeclampsia
Preeclampsia is a common condition unique to pregnant women. Previous studies have suggested that several cytokines may contribute to defective placental invasion and endothelial damage in this condition. We investigated the influence of four single nucleotide polymorphisms (SNPs) in the promoters of IL-6 (-572G/C, -597G/A, and -174G/C) and IL-10 (-592A/C) on suscep.. Read More»
Genet. Mol. Res. 16(1): gmr16018588
DOI: 10.4238/gmr16018588
Sperm retrieval from patients with nonmosaic Klinefelter�s syndrome by semen cytologyexamination
Successful sperm retrieval from ejaculates of nonmosaic Klinefelter’s syndrome (KS) patients by using semen cytology examination was described in this report. The clinical parameters of KS patients with sperm compared to patients without sperm were described. One hundred and fifty-one patients were proven to suffer from KS by chromosomal analysis using G-bandi.. Read More»
Genet. Mol. Res. 13(1): http://dx.doi.org/2014.March.17.12
DOI: http://dx.doi.org/10.4238/2014.March.17.12
Meta-analysis demonstrates no association between p53 codon 72 polymorphism and prostate cancer risk
We examined whether p53 codon 72 polymorphism confers prostate cancer risk by conducting a meta-analysis. Two investigators independently searched the Pubmed, Embase and CBM databases. This meta-analysis was made of seven case-control studies, that included 892 prostate cancer cases and 1020 healthy controls. Meta-analysis results based on all the studies showed no .. Read More»
Genet. Mol. Res. 10(4): 2011.November.29.3
DOI: 10.4238/2011.November.29.3
miR-1 association with cell proliferation inhibition and apoptosis in vestibular schwannoma by targeting VEGFA
A growing body of research has demonstrated the tumor suppressive function of microRNA (miR)-1 in many cancers. Our study aimed to investigate its role in vestibular schwannoma (VS). We examined miR-1 expression in 95 VS specimens and 79 normal vestibular nerves using quantitative real-time polymerase chain reaction. Moreover, miR-1 mimics, miR-1 inhibitors, and neg.. Read More»
Genet. Mol. Res. 15(4): gmr15048923
DOI: 10.4238/gmr15048923
Cloning and characterization of the drought-resistance OsRCI2-5 gene in rice (Oryza sativa L.)
The genomic expression profile of the super-hybrid rice Liangyoupeijiu female parent Pei’ai 64S in different tissues at different developmental stages under low temperature, drought, and high temperature stresses were detected using an Affymetrix GeneChip Rice Genome Array to screen upregulated and downregulated genes. In this study, we screened the drought-re.. Read More»
Genet. Mol. Res. 13(2): http://dx.doi.org/2014.May.23.13
DOI: http://dx.doi.org/10.4238/2014.May.23.13
Isolation and characterization of microsatellite markers for Axonopus compressus (Sw.) Beauv. (Poaceae) using 454 sequencing technology
Axonopus compressus (Sw.) Beauv. is a perennial herb widely used as a garden lawn grass. In this study, we used Roche 454 pyrosequencing, combined with the magnetic bead enrichment method FIASCO, to isolate simple sequence repeat markers from the A. compressus genome. A total of 1942 microsatellite loci were identified, with 53,193 raw sequencing reads. One hundred microsatellite loci were sele.. Read More»
Genet. Mol. Res. 14(2): 2015.May.11.2
DOI: 10.4238/2015.May.11.2
Molecular cloning and immune response analysis of putative variable lipoproteins from Mycoplasma mycoides subsp capri
Mycoplasma mycoides subsp capri is the cause of goat “MAKePS” (Mastitis, Arthritis, Keratoconjunctivitis, Pneumonia, Septicemia) syndrome. We identified three genes (GL_ 000459; 000461; 000462) as variable lipoprotein genes in the M. mycoides subsp capri str. PG3 genome by genomic information and comparative genomic analyses. To study the role of variabl.. Read More»
Genet. Mol. Res. 13(1): http://dx.doi.org/2014.March.12.5
DOI: http://dx.doi.org/10.4238/2014.March.12.5
Novel splice variants of the bovine PCK1 gene
Phosphoenolpyruvate carboxykinase 1 (PCK1), also named PEPCK-C, is a multiple-function gene that is involved in gluconeogenesis, glyceroneogenesis, reproduction, female fertility, and development of obesity and diabetes. How its many functions are regulated was largely unknown. Therefore, we investigated mRNA expression and possible splice variants of PCK1 by screening cDNA in nine tissues from.. Read More»
Genet. Mol. Res. 12(3): 2013.September.27.4
DOI: 10.4238/2013.September.27.4
De novo DNA methylation of the paternal genome in 2-cell mouse embryos
The developmental dynamics of DNA methylation events have been well studied. Active demethylation of the paternal genome occurs in the zygote, passive demethylation occurs during cleavage stages, and de novo methylation occurs by the blastocyst stage. It is believed that the paternal genome has lower levels of methylation during early development than the maternal genome. However, in this study.. Read More»
Genet. Mol. Res. 13(4):
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