L.H. Zhang
The effect of EPS to LPS injure RAW264.7 cell NF-?ºB and MAPK signaling pathway
This study effects of Echinacea polysaccharide(EPS) to Lipopolysaccharides(LPS) injure RAW264.7 cell NF-κB and MAPK signaling pathway. The test was divided into blank groupã?LPS group and 100 mu g/mL EPS + LPS group, The respectively extract Cytoplasm protein and nucleoprotein. After Gel electrophoresis, the Western Blot detected NF-κB, p-p65, I&kapp.. Read More»
Genet. Mol. Res. 16(4): gmr16039846
DOI: 10.4238/gmr16039846
Contributions of polymorphisms in miR146a, miR196a, and miR499 to the development of hepatocellular carcinoma
Hepatocellular carcinoma is one of the most common malignant tumors worldwide; it is estimated that there were 782,000 new cases in 2012. MicroRNAs (miRNAs) play an important role in carcinogenesis by regulating oncogenes and tumor suppressors. We investigated the role of miR-146a, miR-196a2, and miR-499 polymorphisms in the risk of hepatocellular carcinoma in a Chi.. Read More»
Genet. Mol. Res. 15(3): gmr.15038582
DOI: 10.4238/gmr.15038582
Association between polymorphisms in insulin-like growth factor-1 and risk of osteoporosis
We conducted a case-control study to assess the relationship between rs35767, rs2288377, and rs5742612 insulin-like growth factor-1 (IGF-1) and osteoporosis risk in a Chinese female population. The genotypes of rs35767, rs2288377, and rs5742612 of IGF-1 were determined by polymerase chain reaction-restriction fragment length polymorphism. Patients with osteoporosis were more likely to have drin.. Read More»
Genet. Mol. Res. 14(3): 2015.July.13.10
DOI: 10.4238/2015.July.13.10
IL-6-174G/C and IL-6-572C/G polymorphisms are associated with increased risk of coronary artery disease
We conducted this case-control study to investigate the genetic role of IL-1β+3954C/T, IL-6-174G/C, IL-6-572C/G, IL-10-1082A/G, and IL-10-819C/T in the development of coronary artery disease (CAD) in a Chinese population. Polymorphisms IL-1β+3954C/T, IL-6-174G/C, IL-6-572C/G, IL-10-1082A/G, and IL-10-819C/T were determined by polymerase chain reaction restriction fragment length polym.. Read More»
Genet. Mol. Res. 14(3): 2015.July.28.12
DOI: 10.4238/2015.July.28.12
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