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M. Han

Publications of : M. Han
Human Genetics   Research Article

Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population

IL-17 is associated with the occurrence and development of laryngeal cancer. However, no study has reported the association between IL-17 polymorphisms and laryngeal cancer susceptibility. Therefore, we analyzed the association of three polymorphism loci (rs2275913, 197 G/A; rs3748067, 383 A/G; and rs763780, 7488 T/C) of IL-17A and IL-17F with laryngeal cancer in th.. Read More»

Genet. Mol. Res. 16(1): gmr16019076

DOI: 10.4238/gmr16019076

Plant Genetics   Research Article

Effect of temperature on endogenous hormone levels and opposite phyllotaxy in maize leaf primordial

    H. Ye, G.M. Han, Q. Ma, Y.Q. Tan, H.Y. Jiang, S.W. Zhu and B.J. Cheng

Newly identified maize (Zea mays) mutants with opposite leaf phyllotaxy are important in the study of the maize crop. Previous studies have revealed the developmental mechanism of opposite phyllotaxy on the physiological, cellular, and molecular levels. However, there have been few reports regarding the effects of changes in endogenous hormone levels in maize leaf primordia under different cond.. Read More»

Genet. Mol. Res. 14(4): 2015.December.16.2

DOI: 10.4238/2015.December.16.2

Human Genetics   Research Article

Relationship between genetic polymorphisms in MCP-1, CCR-2, and non-small-cell lung cancer in the Han nationality of Northern China

    L. Yang,J. Wang,F.-G. Li,M. Han,X.-J. Chang and Z.-T. Wang

Lung cancer is a common malignant tumor worldwide and is now the leading cause of cancer-related deaths. Monocyte chemoattractant protein 1 (MCP-1) and its receptor chemokine receptor 2 (CCR-2) are important chemokines. We examined the polymorphisms of 338 unrelated patients with non-small cell lung carcinoma (NSCLC) and 200 unrelated healthy controls of Han nationality in Northern China using .. Read More»

Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.22.2

DOI: http://dx.doi.org/10.4238/2015.April.22.2

Human Genetics   Research Article

Evaluation of the semen swim-up method for bovine sperm RNA extraction

    C.M. Han, R. Chen, T. Li, X.L. Chen, Y.F. Zheng, M.T. Ma and Q.H. Gao

Isolation of high-quality RNA is important for assessing sperm gene expression, and semen purification methods may affect the integrity of the isolated RNA. This study evaluated the effectiveness of the sperm swim-up method for seminal RNA isolation. Frozen semen samples in straws from three bulls of proven fertility were purified by the swim-up method. RNA extracti.. Read More»

Genet. Mol. Res. 15(2): gmr.15027713

DOI: 10.4238/gmr.15027713

Plant Genetics   Research Article

Comparative genomic hybridization analysis of rice dwarf mutants induced by gamma irradiation

    J.E. Hwang, S.-H. Kim, I.J. Jung, S.M. Han, J.-W. Ahn, S.-J. Kwon, S.H. Kim, S.-Y. Kang, D.S. Kim and J.-B. Kim

Comparative genomic hybridization (CGH) is a powerful tool used to analyze changes in copy number, polymorphisms, and structural variations in the genome. Gene copy number variation (CNV) is a common form of natural diversity in the genome, which can create new genes and alter gene structure. Thus, CNVs may influence phenotypic variation and gene expression. In this.. Read More»

Genet. Mol. Res. 15(4): gmr15049092

DOI: 10.4238/gmr15049092

Microbial Genetics   Research Article

Purification, characterization, and heterologous expression of an antifungal protein from the endophytic Bacillus subtilis strain Em7 and its activity against Sclerotinia sclerotiorum

    N.N. Wang, X.N. Gao, X. Yan, Z.P. Li, Z.S. Kang, L.L. Huang and Q.M. Han

An antifungal protein exhibiting a high activity against Sclero­tinia sclerotiorum in vivo was purified by ammonium sulfate precipitation, hydrophobic chromatography, and gel filtration chromatography from the culture filtrate of the endophytic Bacillus subtilis strain Em7. The protein was characterized as a β-1,3-1,4-glucanase according to amino acid analy.. Read More»

Genet. Mol. Res. 14(4): 2015.November.30.27

DOI: 10.4238/2015.November.30.27

Medical Genetics   Research Article

Cyclin D1 G870A polymorphism is associated with an increased risk of multiple myeloma

    S. Wang, Y. Huang, R. Su, Z. Fang and M. Han

Cyclin D1 is an important cell cycle regulator implicated in the pathogenesis of many cancer types. In particular, translocation and overexpression of cyclin D1 are common events in multiple myeloma (MM), suggesting that it may drive the initiation and progression of this malignancy. However, the association between genetic polymorphisms of cyclin D1 and the risk for developing MM remains poorl.. Read More»

Genet. Mol. Res. 14(2): 2015.June.1.2

DOI: 10.4238/2015.June.1.2

Plant Genetics   Research Article

Genome-wide expression analysis of a rice mutant line under salt stress

    K.J. Lee, S.-J. Kwon, J.E. Hwang, S.M. Han, I. Jung, J.-B. Kim, H.-I. Choi, J. Ryu and S.-Y. Kang

Salinity is a major environmental stress to plants. In this study, the ability of plants to tolerate salt was investigated by studying growth, physiological characteristics, and expression levels of genes related to the salt-stress response in the salt-tolerant rice mutant (Till-II-877), which was derived from γ-ray irradiation. Compared to plants grown under .. Read More»

Genet. Mol. Res. 15(4): gmr15048833

DOI: 10.4238/gmr15048833

Plant Genetics   Research Article

Transcriptome analysis and anthocyanin-related genes in red leaf lettuce

    Y.Z. Zhang*, S.Z. Xu*, Y.W. Cheng, H.Y. Ya and J.M. Han

This study aimed to analyze the transcriptome profile of red lettuce and identify the genes involved in anthocyanin accumulation. Red leaf lettuce is a popular vegetable and popular due to its high anthocyanin content. However, there is limited information available about the genes involved in anthocyanin biosynthesis in this species. In this study, transcriptomes of 15-day-old seedlings and 40.. Read More»

Genet. Mol. Res. 15(1): gmr.15017023

DOI: 10.4238/gmr.15017023

Plant Genetics   Research Article

Introgression of cotton leaf curl virus-resistant genes from Asiatic cotton (Gossypium arboreum) into upland cotton (G. hirsutum)

    S. Ahmad, K. Mahmood, M. Hanif, W. Nazeer, W. Malik, A. Qayyum, K. Hanif, A. Mahmood and N. Islam

Cotton is under the constant threat of leaf curl virus, which is a major constraint for successful production of cotton in the Pakistan. A total of 3338 cotton genotypes belonging to different research stations were screened, but none were found to be resistant against the Burewala strain of cotton leaf curl virus (CLCuV). We explored the possibility of transferring.. Read More»

Genet. Mol. Res. 10(4): 2011.October.7.2

DOI: 10.4238/2011.October.7.2