Mir Davood Omrani
Investigation of the role of apoptosis, necroptosis and DNA damage signaling pathways in multiple sclerosis
Multiple sclerosis (MS) as the most common autoimmune disorder in the central nervous system is a major health problem. MS is a complex disease with multiple environmental and genetic factors participating in it. In the present study, we evaluated the expression of 3 genes named BCL2, CASP2 and CASP8 in peripheral blood of 50 MS patients and 50 healthy controls to investigate the role of apopto.. Read More»
Genet. Mol. Res. 17(4): http://dx.doi.org/gmr16039937
DOI: http://dx.doi.org/10.4238/gmr16039937
NNT and NNT-AS1 expression levels are not different between bipolar patients and healthy subjects
Nicotinamide nucleotide transhydrogenase (NNT) participates in redox and energy interconnections. Nnt silencing in N27 dopaminergic cells has changed basal, extra, and greatest mitochondrial oxygen absorption rates and made these cell vulnerable to constant upsurges in H2O2. NNT-antisense RNA1 (NNT-AS1) is transcribed from the opposite stand of NNT gene and is possibly involved in regulation of.. Read More»
Genet. Mol. Res. 18(1):
The clinical significance of miR-7-5p downregulation in gastric dysplasia and gastric cancer tissue
miRNAs have been involved in the pathogenesis of several cancers such as gastric cancer (GC.). In the following study we analyzed the expression of miR-7 in gastric cancer samples compared non-tumor tissues and gastric dysplasia (GD) samples with patients’ clinico-pathological data and its potential as diagnostic biomarker. We first analyzed its expression by real-time qRT– PCR in h.. Read More»
Genet. Mol. Res. 18(4):
Expression analysis of OIP5-AS1 in bladder tissues
Long non-coding RNAs (lncRNAs) have crucial roles in regulation of many aspects of cell functions which are related with carcinogenesis process. The lncRNA Opa Interacting Protein 5-antisense 1 (OIP5-AS1) is among lncRNAs whose roles in some human malignancies have been elucidated. In the current study, we aimed at identification of the role of this lncRNA in bladder cancer. Expression level of.. Read More»
Genet. Mol. Res. 18(1):
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