Genet. Mol. Res. ():

Borax-induced apoptosis in HepG2 cells involves p53, Bcl-2, and Bax

Y. Wei1, F.J. Yuan, W.B. Zhou, L. Wu, L. Chen, J.J. Wang and Y.S. Zhang

Borax, a boron compound and a salt of boric acid, is known to inhibit the growth of tumor cells. HepG2 cells have been shown to be clearly susceptible to the anti-proliferative effects of borax. However, the specific mechanisms regulating this effect are poorly understood. This study aimed to investigate the pathways underlying the growth inhibition induced by borax.. Read More»

Genet. Mol. Res. 15(2):

Molecular cloning and characterization, and prokaryotic expression of the GnRH1 gene obtained from Jinghai yellow chicken

T. Zhang, G.X. Zhang, K.P. Han, Y. Tang, J.Y. Wang, Q.C. Fan, X.S. Chen, Y. Wei and Y.J. Wang

The gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Recent studies have reported the occurrence of GnRH molecular variants in numerous species. In this study, the GnRH1 gene from Jinghai yellow chicken was cloned by reverse transcriptase-polymerase chain reaction and transformed into BL.. Read More»

Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.31.14

DOI: http://dx.doi.org/10.4238/2015.March.31.14

Cloning and expression of an APETALA1-like gene from Nelumbo nucifera

D.Z. Kong, X.Y. Shen, B. Guo, J.X. Dong, Y.H. Li and Y.P. Liu

The objective of this study was to clone the full-length cDNA of the APETALA1 (AP1) gene from lotus and analyze its sequence and expression pattern. The full-length cDNA sequence of the NnAP1 gene was amplified from the petals of Nelumbo nucifera ‘Hongxia’ using RT-PCR and rapid amplification of cDNA ends. Bioinformatic methods were used to analyze the sequence characteristics of th.. Read More»

Genet. Mol. Res. 14(2): 2015.June.18.24

DOI: 10.4238/2015.June.18.24

Cross-species amplification and polymorphism of microsatellite loci in Helicoverpa armigera and Helicoverpa zea (Lepidoptera: Noctuidae) in Brazilian cropping systems

N.A. Leite, A.S. Corrêa, A. Alves-Pereira, J.B. Campos, M.I. Zucchi and C. Omoto

The Old World bollworm Helicoverpa armigera (Hübner) was recently discovered in Brazil. This species is closely related to the New World bollworm H. zea (Boddie), and mating between these species has already been reported under laboratory conditions. Here, we tested the cross-species amplification of 20 microsatellite (SSR) loci in field populations of H. armig.. Read More»

Genet. Mol. Res. 15(2): gmr.15027890

DOI: 10.4238/gmr.15027890

Estrogen receptor 1 PvuII and XbaI polymorphisms and susceptibility to Alzheimer�s disease: a meta-analysis

Y.H. Lee and G.G. Song

The aim of this study was to explore whether estrogen receptor 1 (ESR1) PvuII and XbaI polymorphisms are associated with susceptibility to Alzheimer’s disease (AD). We conducted a meta-analysis of the associations between AD and ESR1 PvuII and XbaI polymorphisms as well as haplotypes of the ESR1 PvuII and XbaI polymorphisms. A total of 1359 patients and 1387 controls from 9 studies on the.. Read More»

Genet. Mol. Res. 14(3): 2015.August.10.17

DOI: 10.4238/2015.August.10.17

Genetic progress in oat associated with fungicide use in Rio Grande do Sul, Brazil

D.N. Follmann, A. Cargnelutti Filho, A.D. Lúcio, V.Q. de Souza, M. Caraffa and C.A. Wartha

The State of Rio Grande do Sul (RS) is the largest producer of oat in Brazil with the aid of consolidated breeding programs, which are constantly releasing new cultivars. The main objectives of this study were to: 1) evaluate the annual genetic progress in grain yield and hectoliter weight of the oat cultivars in RS, with and without fungicide use on aerial parts of.. Read More»

Genet. Mol. Res. 15(4): gmr15049390

DOI: 10.4238/gmr15049390

Effect of isodillapiole on the expression of the insecticide resistance genes GSTE7 and CYP6N12 in Aedes aegypti from central Amazonia

V.S. Lima, A.C. Pinto and M.S. Rafael

The yellow fever mosquito Aedes (Stegomyia) aegypti is the main vector of dengue arbovirus and other arboviruses. Dengue prevention measures for the control of A. aegypti involve mainly the use of synthetic insecticides. The constant use of insecticides has caused resistance in this mosquito. Alternative studies on plant extracts and their products have been conducted with the aim of controllin.. Read More»

Genet. Mol. Res. 14(4): 2015.December.11.20

DOI: 10.4238/2015.December.11.20

Genetic diversity of gabiroba based on random amplified polymorphic DNA markers and morphological characteristics

E.S. de Assis, E.F. dos Reis, J.F.N. Pinto, L.A.S. Contim and L.A.S. Dias

The fragmentation of the original vegetation of the Cerrado biome, caused by the expansion of agricultural areas, mainly in central-west Brazil, calls for an assessment of the native population of this vegetation, especially of the species of interest for domestication and sustainable use. The purpose of this study was to characterize the genetic diversity of 140 gabiroba mother plants (Campoma.. Read More»

Genet. Mol. Res. 12(3): 2013.March.11.7

DOI: 10.4238/2013.March.11.7

Genetic adaptations to local environments: Evolutionary significance and implications for conservation and human health

• Poh-San Lai

Genet. Mol. Res. 23(3):