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M.P. de Morais

Publications of : M.P. de Morais
Human Genetics   Research Article

Polymorphisms of GSTM1 and GSTT1 genes in symptomatic atherosclerotic patients with hypertension and/or type 2 diabetes mellitus

Atherosclerosis is a chronic inflammatory condition and originates due to the accumulation of lipids in the innermost layer of the arteries. It is often related due to other underlying diseases, such as systemic arterial hypertension and type 2 diabetes mellitus, which may be the cause or may contribute to a worse prognosis of atherosclerosis. Such diseases also hav.. Read More»

Genet. Mol. Res. 16(4): gmr16039836

DOI: 10.4238/gmr16039836

Human Genetics   Research Article

Male idiopathic infertility and the TP53 polymorphism in codon 72

    M.P. de Morais, R.F. Curado, K.S.F. e Silva, K.K.V.O. Moura and J.T. Arruda

Many environmental agents affect the development of male germ cells at different stages. Apoptosis is common during normal spermatogenesis; it plays an important role in controlling the number of germ cells and the disposal of defective stem cells to produce functional sperm. The presence of p53 in primary spermatocytes suggests that it plays a role in the prophase .. Read More»

Genet. Mol. Res. 15(4): gmr15048882

DOI: 10.4238/gmr15048882

Human Genetics   Research Article

GSTM1 polymorphism in patients with clinical manifestations of atherosclerosis

    D.A. Rodrigues, J.V.M. Martins, K.S.F. e Silva, I.R. Costa, M.H. Lagares, F.L. Campedelli, A.M. Barbosa, M.P. de Morais and K.K.V.O. Moura

Atherosclerosis is characterized by lesions, called atheroma or atheromatous plaques, in the inner layer of blood vessels, which block the vascular lumen and weaken the underlying tunica media. Several modifiable and non-modifiable risk factors for the development of atherosclerosis exist. The modifiable risk factors include hypertension, smoking, obesity, high LDL .. Read More»

Genet. Mol. Res. 16(1): gmr16019101

DOI: 10.4238/gmr16019101

Human Genetics   Research Article

Polymorphism of the gene eNOS G894T (Glu298Asp) in symptomatic patients with aterosclerosis

Atherosclerotic and its cardiovascular complications are responsible for 17.5 million deaths a year, according to the World Health Organization. There is consensus that atherosclerosis involves multiple pathogenic processes initiated by endothelial dysfunction, with inflammation and vascular proliferation determining alterations in the matrix, with consequent format.. Read More»

Genet. Mol. Res. 16(2): gmr16029550

DOI: 10.4238/gmr16029550