Viticulture presents a number of economic and social advantages, such as increasing employment levels and fixing the labor force in rural areas. With the aim of initiating a program of genetic improvement in grapevine from the State University of the state of Rio de Janeiro North Darcy Ribeiro, genetic diversity between 40 genotypes (varieties, rootstock, and specie.. Read More»
Genet. Mol. Res. 16(2): gmr16029586
DOI: 10.4238/gmr16029586
Ketamine is a dissociative anesthetic agent that has been widely used in surgery and for relieving pain in chronic cancer patients. We applied ketamine to breast cancer cell line MDA-MB-231 to detect the effect of treatment and molecular mechanisms involved. We found that ketamine can upregulate the level of anti-apoptosis protein Bcl-2, which promotes breast cancer cell invasion and proliferat.. Read More»
Genet. Mol. Res. 12(2): 2013.January.4.7
DOI: 10.4238/2013.January.4.7
Both rheumatoid arthritis (RA) and osteoarthritis (OA) are complex diseases. Studies and treatment of RA and OA have mainly focused on individual factors. However, there is still no clear understanding of their causes and adequate treatment alternatives are still being sought. We applied gene set-enrichment analysis to microarray datasets of RA and OA to look for regulatory mechanisms. We found.. Read More»
Genet. Mol. Res. 12(3): 2013.March.11.3
DOI: 10.4238/2013.March.11.3
We investigated 2 Chinese families with dyschromatosis symmetrica hereditaria (DSH) and search for mutations in the adenosine deaminase acting on RNA1 (ADAR1) gene in these 2 pedigrees. We performed a mutation analysis of the ADAR1 gene in 2 Chinese families with DSH and reviewed all articles published regarding ADAR1 mutations reported since 2003 by using PubMed. By direct sequencing, a 2-nucl.. Read More»
Genet. Mol. Res. 12(3): 2013.January.4.18
DOI: 10.4238/2013.January.4.18
Gene polymorphism of vitamin D-binding protein (VDBP) correlates with chronic obstructive pulmonary disease (COPD), but the results remain inconclusive. We aimed to explore the association between VDBP gene polymorphism and COPD. We searched MEDLINE, Embase, Web of Science, and China National Knowledge Infrastructure for publications addressing the association between VDBP gene polymorphism and.. Read More»
Genet. Mol. Res. 14(3): http://dx.doi.org/2015.September.9.16
DOI: http://dx.doi.org/10.4238/2015.September.9.16
The application and clinical significance of carbon nanoparticle lymph tracer in the VI region (central region) lymph node dissection of differentiated thyroid cancer was investigated. Eighty patients with differentiated thyroid cancer were equally divided into the carbon nanoparticle-marked group (ipsilateral thyroid injection) and the control group (no injection)... Read More»
Genet. Mol. Res. 13(2): http://dx.doi.org/2014.April.30.4
DOI: http://dx.doi.org/10.4238/2014.April.30.4
We used next-generation sequencing technology to characterize 19 genomic simple sequence repeat (SSR) markers and 11 expressed sequence tag (EST) SSR markers from Leuciscus leuciscus baicalensis, a small freshwater fish that is widely distributed in Xinjiang, China. Primers were used to test for polymorphisms in three L. leuciscus baicalensis populations in Xinjiang.. Read More»
Genet. Mol. Res. 16(2): gmr16029376
DOI: 10.4238/gmr16029376
Previous reports identified an association between sarcoidosis and an insertion/deletion (I/D) polymorphism in angiotensin-converting enzyme. Our meta-analysis of articles published between March 1996 and June 2013 identified studies in the PubMed, EMBASE, and the China National Knowledge Infrastructure databases. We examined whether angiotensin-converting enzyme polymorphisms influence sarcoid.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.17.8
DOI: http://dx.doi.org/10.4238/2015.April.17.8
Genetics and Molecular Research received 56184 citations as per google scholar report