P. Xu
Molecular cloning and differential expression of the glucocorticoid receptorgene in the estuarine tapertail anchovy Coilia nasus
To understand the regulation of the glucocorticoid receptor gene (Gcr) during loading and transport stress in fish, the Gcr gene of Coilia nasus was cloned. Gcr in C. nasus is expressed strongly in the liver and muscle, and less stronglyin the gills, brain, spleen, intestine, trunk kidney, and head kidney. Gcr expression in both the liver and muscle was increased by.. Read More»
Genet. Mol. Res. 16(2): gmr16029125
DOI: 10.4238/gmr16029125
Investigation of single nucleotide polymorphisms in phosphodiesterase 4D gene in Mongol and Han patients with ischemic stroke in Inner Mongolia
We investigated single nucleotide polymorphisms (SNP) at 87 sites of the phosphodiesterase 4D (PDE4D) gene in Mongol and Han patients with ischemic stroke in Inner Mongolia. SNPs in 226 patients with ischemic stroke (case group, 110 Mongol patients, 116 Han patients) and 220 patients without neurological disease (control group, 102 Mongol patients, 118 Han patients) were detected by polymerase .. Read More»
Genet. Mol. Res. 14(3): 2015.August.28.13
DOI: 10.4238/2015.August.28.13
Single nucleotide polymorphisms of Ã?Â?6-desaturase and Elovl5 segments and their associations with common carp (Cyprinus carpio) growth traits
Highly unsaturated fatty acids (HUFAs) are crucial for the nutritional health, physiology, and reproduction of vertebrates. The Δ6-desaturase and Elovl5 elongase genes produce essential enzymes in the biosynthetic pathway of HUFAs. Single nucleotide polymorphism (SNP) analysis of genes functionally related to the growth traits of the common carp (Cyprinus carpio var. Jian) can provide use.. Read More»
Genet. Mol. Res. 14(4): 2015.October.21.4
DOI: 10.4238/2015.October.21.4
Effect of siRNA targeting HER2/neu on the proliferation and viability of prostate cancer PC-3M cells
The aim of this study was to investigate the effect of a small interfering RNA (siRNA) targeting human epidermal growth factor receptor 2 (HER2/neu) on the proliferation and viability of prostate cancer PC-3M cells. Chemically synthesized siRNA targeting HER2/neu was transfected into PC-3M cells by using liposomes, and cells transfected with empty liposomes, a negative siRNA sequence, or nothin.. Read More»
Genet. Mol. Res. 14(4): 2015.December.16.14
DOI: 10.4238/2015.December.16.14
Identification of smut-responsive genes in sugarcane using cDNA-SRAP
Sugarcane smut, caused by the fungus Sporisorium scitamineum, is one of the main diseases that affect sugarcane worldwide. In the present study, the cDNA-SRAP technique was used to identify genes that are likely to be involved in the response of sugarcane to S. scitamineum infection. In total, 21 bands with significant differential expression during cDNA-SRAP analysis were cloned and sequenced... Read More»
Genet. Mol. Res. 14(2): 2015.June.18.23
DOI: 10.4238/2015.June.18.23
Differences in numbers of termicins expressed in two termite species affected by fungal contamination of their environments
Termicin is a defensin-like antimicrobial peptide of termites that has strong antifungal activity. Fifty-six different termicin mRNAs encoding 46 different peptides were amplified and identified from Odontotermes formosanus (Termitidae), a species that inhabits environments with a large variety of microbial fauna. In contrast, only 38 different termicin mRNAs encoding 21 different peptides were.. Read More»
Genet. Mol. Res. 11(3): 2012.May.10.2
DOI: 10.4238/2012.May.10.2
Polymorphisms associated with egg number at 300 days of age in chickens
We looked for variations that could be associated with chicken egg number at 300 days of age (EN300) in seven genes of the hypothalamic-pituitary-gonadal axis, including gonadotrophin-releasing hormone-I (GnRH-I), GnRH receptor (GnRHR), neuropeptide Y (NPY), dopamine D2 receptor (DRD2), vasoactive intestinal polypeptide (VIP), VIP receptor-1 (VIPR-1), prolactin (PRL.. Read More»
Genet. Mol. Res. 10(4): 2011.October.3.5
DOI: 10.4238/2011.October.3.5
Acidic and basic fibroblast growth factor expression levels in cervical cancer and their effects on tumor cell proliferation
Fibroblast growth factors (FGFs) play important roles in angiogenesis, wound healing, embryonic development, and endocrine signaling pathways. Increasingly, recent studies have reported aberrant FGF expression in various malignancies. However, the involvement of FGFs in cervical carcinoma pathogenesis remains unclear. We aimed to investigate expression of acidic (aF.. Read More»
Genet. Mol. Res. 15(4): gmr15049043
DOI: 10.4238/gmr15049043
Prediction of disease-related microRNAs by incorporating functional similarity and common association information
The identification of human disease-related microRNAs (miRNAs) is important for understanding the pathogenesis of diseases, but to do this experimentally is a costly and time-consuming process. Computational prediction of disease-related miRNA candidates is a valuable complement to experimental studies. It is essential to develop an effective prediction method to pr.. Read More»
Genet. Mol. Res. 13(1): 2014.March.24.5
DOI: 10.4238/2014.March.24.5
Screening potential SSR markers of the anadromous fish Coilia nasus by de novo transcriptome analysis using Illumina sequencing
RNA-Seq technology has been widely applied to transcriptomics, genomics, molecular marker development, and functional gene studies. In the genome, microsatellites are simple sequence repeats (SSR) with a high degree of polymorphism that are used as DNA markers in many molecular genetic studies. Using traditional methods such as magnetic bead enrichment, only a few microsatellite marke.. Read More»
Genet. Mol. Res. 14(4): 2015.November.13.1
DOI: 10.4238/2015.November.13.1
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