Q. Song
The effect of acetate Ringer's solution on inflammatory factors and NF-�ºB signal pathway in the liver of hemorrhagic shock rats
Purpose: To investigate the effect of resuscitation with acetated Ringer's solution during hemorrhagic shock (HS) on inflammatory factors and nuclear factor κB (NF-κB) signaling pathway in liver tissue. Methods: In this study, a rat HS model was established. HS rats received acetated Ringer's solution, lactated Ringer's solution and saline for fluid resuscitation. Inflammatory facto.. Read More»
Genet. Mol. Res. 17(2): gmr16039906
DOI: 10.4238/gmr16039906
Influence of adenosine on preservation of porcine pancreas in islet transplantation
Ischemia time during transplantation has greatly restricted the quality and utilization of grafts. To improve the quality of islet transplantation, adenosine was added into the University of Wisconsin (UW) pancreas perfusate to assess its effect on islet yield and function in porcine pancreas. Ten pancreata from donation after cardiac death pigs were obtained and randomly divided into two group.. Read More»
Genet. Mol. Res. 14(4): 2015.December.23.17
DOI: 10.4238/2015.December.23.17
Identification of long non-coding RNA involved in osteogenic differentiation from mesenchymal stem cells using RNA-Seq data
The aim of this study was to identify long non-coding RNA (lncRNA) associated with osteogenic differentiation from mesenchymal stem cells (MSCs) using high-throughput RNA sequencing (RNA-Seq) data. RNA-Seq dataset was obtained from the European Bioinformatics Institute (accession No. PRJEB4496), including two replicates each for immortalized mesenchymal stem cells iMSC#3 cultured in growth medi.. Read More»
Genet. Mol. Res. 14(4): 2015.December.23.14
DOI: 10.4238/2015.December.23.14
Functions of microRNA in response to cocaine stimulation
MicroRNAs (miRNAs) are a type of non-protein-coding single-stranded RNA, which are typically 20-25 nt in length. miRNAs play important roles in various biological processes, including development, cell proliferation, differentiation, and apoptosis. We aimed to detect the miRNA response to cocaine stimulations and their target genes. Using the miRNA expression data G.. Read More»
Genet. Mol. Res. 13(4): 2013.December.4.2
DOI: 10.4238/2013.December.4.2
Genetic polymorphisms and haplotype of hormone-related genes are associated with the risk of breast cancer in Chinese women
Sex hormones play important roles in breast cancer (BC) development. This study investigated associations between BC risk and hormone-related gene variants in Chinese women. In a cohort of 336 patients with histopathologically confirmed BC and 390 age-matched controls, we genotyped seven single nucleotide polymorphisms (SNPs) in five hormone-related genes: estrogen .. Read More»
Genet. Mol. Res. 15(2): gmr.15028640
DOI: 10.4238/gmr.15028640
Association between FTO polymorphism in exon 3 with carcass and meat quality traits in crossbred ducks
The fat mass and obesity-associated gene (FTO) is an excellent candidate gene that affects energy metabolism. Single nucleotide polymorphisms (SNPs) in FTO are associated with carcass and meat quality traits in pigs, cattle, and rabbits. The aim of this study was to investigate the association between novel SNPs in the FTO coding region and carcass and meat quality traits in 95 crossbred ducks,.. Read More»
Genet. Mol. Res. 14(2): 2015.June.18.14
DOI: 10.4238/2015.June.18.14
Nucleotide variation in the Toxoplasma gondii micronemal protein 8 gene
Toxoplasma gondii is a successful opportunistic protozoan distributed worldwide, which can infect all vertebrates, leading to serious infection, blindness, and abortion. Micronemal (MIC) proteins are critically important for T. gondii infection, as they participate in various stages of the Toxoplasma life cycle, including invasion and attachment to host cells. MIC8 .. Read More»
Genet. Mol. Res. 15(2): gmr.15028578
DOI: 10.4238/gmr.15028578
Genetic diversity and classification of Tibetan yak populations based on the mtDNA COIII gene
To determine the level of genetic diversity and phylogenetic relationships among Tibetan yak populations, the mitochondrial DNA cytochrome c oxidase subunit 3 (COIII) genes of 378 yak individuals from 16 populations were analyzed in this study. The results showed that the length of cytochrome c oxidase subunit 3 gene sequences was 781 bp, with nucleotide frequencies of 29.2, 29.4, 26.1, and 15... Read More»
Genet. Mol. Res. 14(1): 2015.March.13.3
DOI: 10.4238/2015.March.13.3
Activation of p38-mitogen-activated protein kinase contributes to ischemia reperfusion in rat brain
Inflammation plays an important role in cerebral ischemia reperfusion, which can cause severe damage to the brain and may lead to cerebral hemorrhage transformation. p38-mitogen-activated protein kinase (p38mapk) has been implicated in the etiology of a number of diseases because it is a cause of inflammation, but comparatively little research has been carried out into its role in the etiology .. Read More»
Genet. Mol. Res. 15(3): gmr.15038492
DOI: 10.4238/gmr.15038492
PI3K-Akt-mTOR signal inhibition affects expression of genes related to endoplasmic reticulum stress
PI3K-Akt-mTOR signaling pathway is associated with endoplasmic reticulum (ER) stress. However, it is not clear how this signaling pathway affects the ER stress. The present study aimed to determine whether the PI3K-Akt-mTOR signaling pathway regulates tunicamycin (TM)-induced increases in mRNA levels of genes involved in the ER stress, to help elucidate the mechanism by which this pathway affec.. Read More»
Genet. Mol. Res. 15(3): gmr.15037868
DOI: 10.4238/gmr.15037868
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