Q.D. Jiang
The effect of EPS to LPS injure RAW264.7 cell NF-�?ºB and MAPK signaling pathway
This study effects of Echinacea polysaccharide(EPS) to Lipopolysaccharides(LPS) injure RAW264.7 cell NF-κB and MAPK signaling pathway. The test was divided into blank groupã�?LPS group and 100 mu g/mL EPS + LPS group, The respectively extract Cytoplasm protein and nucleoprotein. After Gel electrophoresis, the Western Blot detected NF-κB, p-p65, I&kapp.. Read More»
Genet. Mol. Res. 16(4): gmr16039846
DOI: 10.4238/gmr16039846
Attenuated mRNA expression of lipid metabolism genes in primary hepatocytes following lipopolysaccharide treatment in dairy cows
The influence of ruminal acidosis on ruminal microbiology and metabolite production has received considerable attention, but little is known regarding the systemic manifestations that arise from ruminal acidosis. Lipopolysaccharide (LPS) is released in the gastrointestinal tract upon ingestion of high-grain or high-fat diets, and it has been implicated in the etiology of multiple energy- and li.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.17.21
DOI: http://dx.doi.org/10.4238/2015.April.17.21
Leptin mRNA expression in the rat mammary gland at different activation stages
Leptin is expressed in various tissues, suggesting that this protein is effective not only at the central nervous system level, but also peripherically. Recent studies have shown leptin production by other tissues, including the placenta, stomach, and mammary tissues, but there is no information available concerning expression levels of leptin in the rat mammary gla.. Read More»
Genet. Mol. Res. 10(4): 2011.October.21.3
DOI: 10.4238/2011.October.21.3
Effect of puerarin on the expression of NMU, NPY, and POMC genes in the hypothalamus
The hypothalamus is an important component of the nervous system, and neuropeptide Y (NPY), proopiomelanocortin (POMC), and neuromedin U (NMU) are key players in physiological regulation. Puerarin is important for nerve regulation. We investigated the effect of puerarin on the expression of NMU, NPY, and POMC genes in the hypothalamus. The results showed that the puerarin low-dose group and the.. Read More»
Genet. Mol. Res. 15(1): gmr.15017362
DOI: 10.4238/gmr.15017362
Effects of lipopolysaccharide on the stearoyl-coenzyme A desaturase mRNA level in bovine primary hepatic cells
This study aimed to compare the effects of lipopolysaccharide (LPS) on stearoyl-coenzyme A desaturase (SCD) gene expression in mouse primary hepatic cells. To obtain sufficient total RNA, primary hepatic cells were plated on 6-cm diameter-type collagen 1-coated dishes (1 x 106 cells per dish). The test was divided into 6 groups with 6 replications per group. The 6 g.. Read More»
Genet. Mol. Res. 13(2): 2014.January.24.12
DOI: 10.4238/2014.January.24.12
Isolation and identification of bovine primary hepatocytes
The liver is a unique organ that is endowed with a plethora of specialized functions. Most of its functional traits are controlled by hepatocytes. Primary hepatocytes have been used widely in in vitro models to understand the biological processes occurring in the liver. There are a number of methods used to separate hepatocytes, but the cell activity and purity are much lower in this condition... Read More»
Genet. Mol. Res. 12(4): 2013.October.30.3
DOI: 10.4238/2013.October.30.3
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