R. Liu
Differential gene expression in the peripheral blood of Chinese Sanhe cattle exposed to severe cold stress
Livestock is an important food resource for the inhabitants of cold regions, such as northern Asia and alpine regions, where agriculture is limited. In these regions, cold stress largely affects livestock production, thereby reducing the productivity and survival of animals. Despite the importance of breeding cold-tolerant animals, few studies have investigated the .. Read More»
Genet. Mol. Res. 16(2): gmr16029593
DOI: 10.4238/gmr16029593
Expression and significance of miR-21 in multiple myeloma patients
The aim of the present study is to examine the expression level of peripheral mir-21 in multiple myeloma (MM) patients and to determine its clinical significance. MM patients (30), monoclonal gammopathy of undetermined significance (MGUS) patients (14), and normal controls (20) were recruited to determine the serum level of β2-MG, IgA and IgM, IgG, λ, κ, TP, ALB, Hb, LDH, and .. Read More»
Genet. Mol. Res. 15(1): gmr.15016892
DOI: 10.4238/gmr.15016892
Differential expression of luteinizing hormone receptor, androgen receptor and heat-shock protein 70 in the testis of long-distance transported mice
Spermatogenesis, is a complex process of precisely regulated intracellular events, where it is affected by many factors. Long-distance transport of animals is one of the stressors that may influence spermatogenesis and sperm quality. The present study chose luteinizing hormone receptor (LHR), androgen receptor (AR), and heat-shock protein 70 (HSP70) as our target genes to investigate their mRNA.. Read More»
Genet. Mol. Res. 14(3): 2015.August.21.4
DOI: 10.4238/2015.August.21.4
Polymorphisms in GJA1 and their association with growth traits in chicken
This study aimed to screen single nucleotide polymorphisms (SNPs) in the chicken gap junction protein alpha 1 (GJA1) gene, and to investigate their association with five growth traits measured in 269 chickens encompassing Chinese indigenous Beijing-You (BJY) and commercial Cobb broiler (CB) populations. Four variants were detected in the chicken GJA1 gene, in which one synonymous mutation was l.. Read More»
Genet. Mol. Res. 14(4): 2015.December.28.33
DOI: 10.4238/2015.December.28.33
Association between CASP-8 gene polymorphisms and cancer risk in some Asian population based on a HuGE review and meta-analysis
Genetic variation in the CASP-8 gene reportedly can increase cancer susceptibility by regulating tumor cell proliferation and apoptosis. Several studies have investigated this possibility; however, the conclusions remain controversial. We made a Human Genome Epidemiology (HuGE) review and did a meta-analysis to explore the association between CASP-8 gene polymorphisms and cancer risk in Asian p.. Read More»
Genet. Mol. Res. 12(4): 2013.February.28.3
DOI: 10.4238/2013.February.28.3
De novo assembly and characterization of the root transcriptome and development of simple sequence repeat markers in Paphiopedilum concolor
Paphiopedilum orchids (Orchidaceae) have attracted much attention from botanists and horticulturists because of their peculiar leaves and beautiful flowers. Furthermore, the dry roots of Paphiopedilum plants have well-known medicinal uses. However, it is unknown how sensitive and plastic the root genes are to environmental changes or how these environmental changes regulate the biosynthesis of .. Read More»
Genet. Mol. Res. 14(2): 2015.June.9.5
DOI: 10.4238/2015.June.9.5
Protective effect of necrostatin-1 on myocardial tissue in rats with acute myocardial infarction
The aim of this study was to investigate the protective effect of necrostatin-1 on myocardial tissue of acute myocardial infarction (AMI) rats and to provide a basis for necrostatin-1 for the treatment of acute myocardial infarction. AMI rats (45) were established by ligating the anterior descending branch of the left coronary artery. The rats were randomly divided .. Read More»
Genet. Mol. Res. 15(2): gmr.15027298
DOI: 10.4238/gmr.15027298
Proteomic analysis of susceptibility in intestinal stromal tumors
We analyzed the susceptibility of intestinal stromal tumors using cell culture and proteomics. Human SGC7901 gastric cells were selected and divided into a blank control group (untransfected SGC7901 cells), a negative control group [SGC7901 cells transfected with negative interference control-small interfering RNA (siRNA)], and a COOH-terminus tensin-like molecule (CTEN)-siRNA-1 group (SGC7901 .. Read More»
Genet. Mol. Res. 14(4): 2015.October.28.16
DOI: 10.4238/2015.October.28.16
Effects of Sirtuin 1 on the proliferation and osteoblastic differentiation of periodontal ligament stem cells and stem cells from apical papilla
The function of SIRT1 in the proliferation and osteoblastic differentiation of dental stem cells is unclear. The aim of this study was to assess the roles of SIRT1 in these processes using periodontal ligament stem cells (PDLSCs) and stem cells from apical papilla (SCAPs). A defined concentration of resveratrol, an SIRT1 activator, or nicotinamide, an SIRT1 inhibito.. Read More»
Genet. Mol. Res. 15(1): gmr.15015234
DOI: 10.4238/gmr.15015234
Molecular characterization, tissue distribution, and immune reaction expression of karyopherins in the domestic silkworm (Bombyx mori)
Karyopherins, including alpha and beta types, are transport proteins in the eukaryotic cell that carry cargoes across nuclear pore complexes into or out of the nucleus. In this study, full open reading frames of one beta and three alpha types of karyopherin were cloned from cDNA of the domestic silkworm (Bombyx mori). The one beta and three alpha types’ open reading frames were 2661, 1563.. Read More»
Genet. Mol. Res. 14(4): 2015.October.26.1
DOI: 10.4238/2015.October.26.1
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