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R.S. Mascarenhas

Publications of : R.S. Mascarenhas
Human Genetics   Research Article

Characterization of molecular hemoglobin c and beta thalassemia

The hemoglobinopathies are a group of hereditary alterations prevalent in many parts of the world, but significantly affect the Brazilian population for its abundant miscegenation. These alterations in structural genes that cause the formation of hemoglobin variants, and/or regulatory genes, causing thalassemias. Currently, the number of identified abnormal hemoglob.. Read More»

Genet. Mol. Res. 16(4): gmr16039851

DOI: 10.4238/gmr16039851

Medical Genetics   Research Article

Analysis of the prevalence of polymorphisms in the glutathione S transferase gene (GST) in cataract patients from Goi�¢nia

    I.R. Costa, R.S. Mascarenhas, J.F. Corrêa, F.R.B. Oliveira, S.G. Fernandes, F.O. Souza, G.M. dos Reis, A. de P.R. Júnior, D.A. Rodrigues, J.V.M. Martins, K.S.F. e Silva and K.K.V.O. Moura

The aim of this study was to determine the prevalence of polymorphisms in the glutathione S-transferase genes GSTM1 and GSTT1 in patients with lens opacity (cataract). Peripheral blood samples were obtained from male and female patients (N = 23) with cataract. The GSTM1 and GSTT1 polymorphic regions were amplified by polymerase chain reaction, and the amplification products were electrophoresed.. Read More»

Genet. Mol. Res. 15(3): gmr.15038050

DOI: 10.4238/gmr.15038050

Human Genetics   Research Article

Polymorphisms of GSTM1 and GSTT1 genes in symptomatic atherosclerotic patients with hypertension and/or type 2 diabetes mellitus

Atherosclerosis is a chronic inflammatory condition and originates due to the accumulation of lipids in the innermost layer of the arteries. It is often related due to other underlying diseases, such as systemic arterial hypertension and type 2 diabetes mellitus, which may be the cause or may contribute to a worse prognosis of atherosclerosis. Such diseases also hav.. Read More»

Genet. Mol. Res. 16(4): gmr16039836

DOI: 10.4238/gmr16039836

Human Genetics   Research Article

Atherosclerosis: analysis of the eNOS (T786C) gene polymorphism

The coronary arteriosclerotic disease is the most common cardiovascular disease. Atherosclerosis affects large- and medium-sized arteries leading to severe thrombosis or artery stenosis that could evolve to myocardial infarction, ischemic stroke, ischemic injury of kidneys and intestines, and several other life-threatening clinical manifestations. Nitric oxide has b.. Read More»

Genet. Mol. Res. 16(3): gmr16039708

DOI: 10.4238/gmr16039708