Shahram Arsang-Jang

Investigation of the role of apoptosis, necroptosis and DNA damage signaling pathways in multiple sclerosis

• Romina Dastmalchi
• Arezou Sayad
• Mir Davood Omrani
• Soudeh Ghafouri-Fard
• Shahram Arsang-Jang
• Mehrdokht Mazdeh
• Mohammad Taheri

Multiple sclerosis (MS) as the most common autoimmune disorder in the central nervous system is a major health problem. MS is a complex disease with multiple environmental and genetic factors participating in it. In the present study, we evaluated the expression of 3 genes named BCL2, CASP2 and CASP8 in peripheral blood of 50 MS patients and 50 healthy controls to investigate the role of apopto.. Read More»

Genet. Mol. Res. 17(4): http://dx.doi.org/gmr16039937

DOI: http://dx.doi.org/10.4238/gmr16039937

Expression analysis of long non-coding RNAs GSTT1-AS1 and IFNG-AS1 and their target genes in lung cancer

• Farbod Esfandi
• Zabih Mir Hassani
• Shahram Arsang-Jang
• Mohammad Taheri
• Soudeh Ghafouri-Fard

Long non-coding RNAs (lncRNAs) have recently gained attention because of their regulatory roles on expression of genes involved in the immune response and cancer. In the present study, we evaluated expression of two lncRNAs (GSTT1-AS1 and IFNG-AS1) and their target genes (TNFA and IFNG) in human lung cancer samples and their adjacent non-cancerous tissues (ANCTs) to find their putative role in .. Read More»

Genet. Mol. Res. 18(3):