Soudeh Ghafouri-Fard
Investigation of the role of apoptosis, necroptosis and DNA damage signaling pathways in multiple sclerosis
Multiple sclerosis (MS) as the most common autoimmune disorder in the central nervous system is a major health problem. MS is a complex disease with multiple environmental and genetic factors participating in it. In the present study, we evaluated the expression of 3 genes named BCL2, CASP2 and CASP8 in peripheral blood of 50 MS patients and 50 healthy controls to investigate the role of apopto.. Read More»
Genet. Mol. Res. 17(4): http://dx.doi.org/gmr16039937
DOI: http://dx.doi.org/10.4238/gmr16039937
NNT and NNT-AS1 expression levels are not different between bipolar patients and healthy subjects
Nicotinamide nucleotide transhydrogenase (NNT) participates in redox and energy interconnections. Nnt silencing in N27 dopaminergic cells has changed basal, extra, and greatest mitochondrial oxygen absorption rates and made these cell vulnerable to constant upsurges in H2O2. NNT-antisense RNA1 (NNT-AS1) is transcribed from the opposite stand of NNT gene and is possibly involved in regulation of.. Read More»
Genet. Mol. Res. 18(1):
Expression analysis of long non-coding RNAs GSTT1-AS1 and IFNG-AS1 and their target genes in lung cancer
Long non-coding RNAs (lncRNAs) have recently gained attention because of their regulatory roles on expression of genes involved in the immune response and cancer. In the present study, we evaluated expression of two lncRNAs (GSTT1-AS1 and IFNG-AS1) and their target genes (TNFA and IFNG) in human lung cancer samples and their adjacent non-cancerous tissues (ANCTs) to find their putative role in .. Read More»
Genet. Mol. Res. 18(3):
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