X. Tong
Mechanism of pingyangmycin-induced apoptosis of cultured human umbilical vein endothelial cells
In this study, we investigated the effects of pingyangmycin (PYM) on the growth inhibition and apoptosis of human umbilical vein endothelial cells (HUVEC). In this study, we aimed to explore the optimal concentration of PYM to induce the apoptosis of HUVEC and to determine its mechanism of action. After treatment of HUVEC with different concentrations of PYM for 24 .. Read More»
Genet. Mol. Res. 16(2): gmr16029298
DOI: 10.4238/gmr16029298
Role and diagnostic value of gene variants in assessing the risk of chronic obstructive pulmonary disease
Meta-analyses have revealed many positive associations between gene variants and susceptibility to chronic obstructive pulmonary disease (COPD). However, some of those positive results may be false positives. Therefore, we investigated the genetic polymorphisms associated with COPD risk and determined their diagnostic value. We extracted the odds ratio (OR) and 95% .. Read More»
Genet. Mol. Res. 15(2): gmr.15027854
DOI: 10.4238/gmr.15027854
Body color development and genetic analysis of hybrid transparent crucian carp (Carassius auratus)
The aim of this study was to investigate the genetic mechanism of the transparent trait in transparent crucian carp. We observed body color development in transparent crucian carp larvae and analyzed heredity of color in hybrids produced with red crucian carp, ornamental carp, and red purse carp. The results showed that the body color of the newly hatched larvae matured into the adult pattern a.. Read More»
Genet. Mol. Res. 14(2): 2015.April.30.13
DOI: 10.4238/2015.April.30.13
A novel NF1 mutation in a Chinese patient with giant caf�©-au-lait macule in neurofibromatosis type 1 associated with a malignant peripheral nerve sheath tumor and bone abnormality
Neurofibromatosis type 1 (NF1; OMIM#162200) is a common neurocutaneous disorder that is characterized by multiple café-au-lait, skinfold freckling, Lisch nodules, and neurofibromas. Mutations in the NF1 gene, which encodes the neurofibromin protein, have been identified as the pathogenic gene of NF1. In this study, we present a clinical and molecular study of a Chinese patient with giant.. Read More»
Genet. Mol. Res. 11(3): 2012.July.10.6
DOI: 10.4238/2012.July.10.6
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