X. Zhang
Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer
Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function and protein expression. We examined the .. Read More»
Genet. Mol. Res. 16(3): gmr16038826
DOI: 10.4238/gmr16038826
Screening of molecular markers linked to dwarf trait in crape myrtle by bulked segregant analysis
Plant height is one of the most important traits of plant architecture as it modulates both economic and ornamental values. Crape myrtle (Lagerstroemia indica L.) is a popular ornamental woody plant because of its long-lasting mid-summer bloom, rich colors, and diversified plant architecture. These traits also make it an ideal model of woody species for genetic analysis of many ornamental trait.. Read More»
Genet. Mol. Res. 14(2): 2015.April.30.10
DOI: 10.4238/2015.April.30.10
Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury
To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 μg·kg-1·day-1) for 5 days.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.27.25
DOI: http://dx.doi.org/10.4238/2015.April.27.25
Long-term survival of non-small-cell lung cancer patients with EGFR inhibitor treatment
The epidermal growth factor receptor (EGFR) inhibitors gefitinib and erlotinib are effective in the treatment of advanced non-small-cell lung cancer (NSCLC), but the median survival of patients is short. Here, we describe 2 patients with NSCLC receiving conventional chemotherapy and alternative treatment with gefitinib or erlotinib as second-line therapy. The first patient was alive at 8 years .. Read More»
Genet. Mol. Res. 13(4):
Pathology of the lower nasolacrimal duct mucosa at multiple time points after lacrimal retrograde catheterization in rabbit
Lacrimal duct obstruction is a common eye disease, and obstruction of the nasolacrimal duct accounts for over 50% of these cases. Nasolacrimal duct obstruction is usually treated surgically. Lacrimal retrograde catheterization is a novel surgical approach with a high success rate and a relatively high recurrence rate. In this study, we examined the postoperative pathological changes in the lowe.. Read More»
Genet. Mol. Res. 14(3): 2015.July.14.19
DOI: 10.4238/2015.July.14.19
ERCC1 mRNA expression is associated with the clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy
We conducted a prospective study to analyze the expression of the excision repair cross-complementing group 1 (ERCC1) and ribonucleotide reductase subunit M1 (RRM1) genes in 297 Chinese patients with advanced non-small cell lung cancer (NSCLC). The goal of this study was to evaluate these genes as potential biomarkers for prediction of tumor response and clinical outcome. Patients with unresect.. Read More»
Genet. Mol. Res. 13(4): 2014.December.4.16
DOI: 10.4238/2014.December.4.16
Screening and analyzing genes associated with Amur tiger placental development
The Amur tiger is a unique endangered species in the world, and thus, protection of its genetic resources is extremely important. In this study, an Amur tiger placenta cDNA library was constructed using the SMART cDNA Library Construction kit. A total of 508 colonies were sequenced, in which 205 (76%) genes were annotated and mapped to 74 KEGG pathways, including 29.. Read More»
Genet. Mol. Res. 13(3): 2014.September.26.25
DOI: 10.4238/2014.September.26.25
Decreased retinol-binding protein 4 in the sera of patients with end-stage renal disease after kidney transplantation
Retinol-binding protein 4 (RBP4) is a novel adipokine that has been associated with insulin resistance and type 2 diabetes. Patients with end-stage renal disease (ESRD) have very high serum RBP4 levels. However, whether successful kidney transplantation alleviates these elevated serum RBP4 levels is unclear. The serum RBP4 levels of 24 ESRD patients were determined before transplantation and at.. Read More»
Genet. Mol. Res. 13(4):
Molecular cloning and characterization, and prokaryotic expression of the GnRH1 gene obtained from Jinghai yellow chicken
The gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Recent studies have reported the occurrence of GnRH molecular variants in numerous species. In this study, the GnRH1 gene from Jinghai yellow chicken was cloned by reverse transcriptase-polymerase chain reaction and transformed into BL.. Read More»
Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.31.14
DOI: http://dx.doi.org/10.4238/2015.March.31.14
Genetic diversity of Aquilegia (Ranunculaceae) species and cultivars assessed by AFLPs
Species of the genus Aquilegia are exceptionally diverse in their floral morphology and color, commonly known as columbine. They are widely planted ornamentals and are highly attractive for hummingbirds. However, little is known about their genetic diversity. We examined the genetic diversity of the species and cultivars using amplified fragment length polymorphism .. Read More»
Genet. Mol. Res. 10(2): vol10-2gmr1112
DOI: 10.4238/vol10-2gmr1112
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