X.F. Gu
Molecular mapping and candidate gene analysis for resistance to powdery mildew in Cucumis sativus stem
Powdery mildew (PM) of cucumber (Cucumis sativus), caused by Podosphaera xanthii, is a major foliar disease worldwide and resistance is one of the main objectives in cucumber breeding programs. The resistance to PM in cucumber stem is important to the resistance for the whole plant. In this study, genetic analysis and gene mapping were implemented with cucumber inbr.. Read More»
Genet. Mol. Res. 16(3): gmr16039680
DOI: 10.4238/gmr16039680
Association of phosphodiesterase 4D gene and interleukin-6 receptor gene polymorphisms with ischemic stroke in a Chinese hypertensive population
Genetic factors have been shown to be associated with the risk of stroke. However, due to individual differences, the extent of the association between genetic factors and stroke varies widely. Hypertension is considered one of the most important risk factors for stroke, but it remains unknown whether the genetic association with stroke in a hypertensive population is the same as that in a non-.. Read More»
Genet. Mol. Res. 14(4): 2015.December.29.50
DOI: 10.4238/2015.December.29.50
Polymorphisms of the myostatin gene (MSTN) and its relationship with growth traits in goat breeds
Mutations in the myostatin (MSTN) gene can inactivate its expression and result in a non-functional protein, which leads to dramatic muscularity and a “double-muscling” phenomenon in many species. Using gene sequencing and polymerase chain reaction-single-strand conformation polymorphism methods, polymorphisms of the MSTN gene were investigated as a candidate marker for growth in 28.. Read More»
Genet. Mol. Res. 12(2): 2013.April.2.12
DOI: 10.4238/2013.April.2.12
Lenalidomide affect expression level of cereblon protein in multiple myeloma cell line RPMI8226
We investigated the mechanisms of action of immunomodulatory drug (lenalidomide) on the protein expression of cereblon (CRBN) and their therapeutic targets in the multiple myeloma cell line RPMI8226. The multiple myeloma cell line RPMI8226 was cultured and treated with different concentrations of lenalidomide and bortezomib to determine the proliferation inhibition rate, apoptosis rate, and pro.. Read More»
Genet. Mol. Res. 14(4): 2015.October.28.19
DOI: 10.4238/2015.October.28.19
Microsatellite marker analysis reveals the distinction between the north and south groups of hard clam (Meretrix meretrix) in China
Meretrix meretrix is one of the important commercial bivalves in China. A total of 198 individual clams were collected from 5 locations characteristic of the clam’s 5 main natural habitats in China, that is, Shandong, Jiangsu, Fujian, Guangdong, and Guangxi. Ten polymorphic microsatellite markers were selected to examine the genetic diversity and identify genetic differences between the 5.. Read More»
Genet. Mol. Res. 14(1): 2015.February.6.23
DOI: 10.4238/2015.February.6.23
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