Y. Li
Molecular cloning and differential expression of the glucocorticoid receptorgene in the estuarine tapertail anchovy Coilia nasus
To understand the regulation of the glucocorticoid receptor gene (Gcr) during loading and transport stress in fish, the Gcr gene of Coilia nasus was cloned. Gcr in C. nasus is expressed strongly in the liver and muscle, and less stronglyin the gills, brain, spleen, intestine, trunk kidney, and head kidney. Gcr expression in both the liver and muscle was increased by.. Read More»
Genet. Mol. Res. 16(2): gmr16029125
DOI: 10.4238/gmr16029125
Novel representation of RNA secondary structure used to improve prediction algorithms
We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the comparative sequence analysis method results and the minimum free-energy model. In the comparati.. Read More»
Genet. Mol. Res. 10(3): vol10-3gmr1181
DOI: 10.4238/vol10-3gmr1181
Different timing and spatial separation of parental chromosomes in intergeneric somatic hybrids between Brassica napus and Orychophragmus violaceus
Experimental and newly formed hybrids and polyploids generated by wide crosses usually show varying degrees of cytological instability. The spatial separation of parental genomes and uniparental chromosome elimination in hybrid cells has been reported in many hybrids from plants and animals. Herein, the behavior of parental genomes in intergeneric somatic hybrids be.. Read More»
Genet. Mol. Res. 13(2): 2014.April.8.3
DOI: 10.4238/2014.April.8.3
MicroRNA-122 is involved in oxidative stress in isoniazid-induced liver injury in mice
Many studies have shown that the pathogenesis of liver injury includes oxidative stress. MicroRNA-122 may be a marker for the early diagnosis of drug-induced liver injury. However, the relationship between microRNA-122 and oxidative stress in anti-tuberculosis drug-induced liver injury remains unknown. We measured changes in tissue microRNA-122 levels and indices of oxidative stress during live.. Read More»
Genet. Mol. Res. 14(4): 2015.October.26.22
DOI: 10.4238/2015.October.26.22
A novel FBN1 heterozygous mutation identified in a Chinese family with autosomal dominant Marfan syndrome
The purpose of this study was to identify the clinical features and mutations in the fibrillin-1 gene (FBN1) in a large Chinese family with autosomal dominant Marfan syndrome (MFS). Seventeen members from a Chinese family of 4 generations were included in the study. All members underwent complete ophthalmic examination. Molecular genetic analysis was performed on all subjects. All exons of FBN1.. Read More»
Genet. Mol. Res. 14(2): http://dx.doi.org/2015.April.27.27
DOI: http://dx.doi.org/10.4238/2015.April.27.27
Post-surgical treatment of a patient with ectopic pheochromocytoma
We report here the course and treatment of a patient with ectopic pheochromocytoma. The patient was cured after treatment with respiratory and circulatory support, multiple-organ protection, and continuous renal replacement therapy (CRRT) for approximately 2 weeks. After misdiagnosis, a patient with ectopic pheochromocytoma who is being treated should undergo aggressive fluid supplementation an.. Read More»
Genet. Mol. Res. 14(1): 2015.March.20.25
DOI: 10.4238/2015.March.20.25
Gene annotation and functional analysis of a newly sequenced Synechococcus strain
Synechococcus sp PCC 7336 represents a newly sequenced strain, and its genome is obviously different from that of other Synechococcus strains. In this analysis, local alignment and annotation databases were constructed and combined with various bioinformatic tools to carry out gene annotation and functional analysis of this strain. From this analysis, we identified .. Read More»
Genet. Mol. Res. 14(4): 2015.October.16.8
DOI: 10.4238/2015.October.16.8
Genetic variations in MOV10 and CACNB2 are associated with hypertension in a Chinese Han population
Human hypertension is a complex, multifactorial disease. Multiple variants associated with hypertension have been identified in the large numbers of genome-wide association studies, meta-analysis, and case-control studies. The present study investigated the association between the single nucleotide polymorphisms (SNPs) of five candidate genes and the susceptibility and prognosis of hypertension.. Read More»
Genet. Mol. Res. 12(4): 2013.December.4.9
DOI: 10.4238/2013.December.4.9
Isolation and characterization of microsatellite markers for Axonopus compressus (Sw.) Beauv. (Poaceae) using 454 sequencing technology
Axonopus compressus (Sw.) Beauv. is a perennial herb widely used as a garden lawn grass. In this study, we used Roche 454 pyrosequencing, combined with the magnetic bead enrichment method FIASCO, to isolate simple sequence repeat markers from the A. compressus genome. A total of 1942 microsatellite loci were identified, with 53,193 raw sequencing reads. One hundred microsatellite loci were sele.. Read More»
Genet. Mol. Res. 14(2): 2015.May.11.2
DOI: 10.4238/2015.May.11.2
A potential indicator of denervated muscle atrophy: the ratio of myostatin to follistatin in peripheral blood
Myostatin is a secreted negative regulator of muscle mass, and follistatin antagonizes the function of several members of the TGF-b family, including myostatin. Previously, myostatin expression was found to be closely associated with atrophy of the gastrocnemius muscle, showing a linear correlation, after sciatic nerve injury. In this study, we investigated the poss.. Read More»
Genet. Mol. Res. 10(4): 2011.October.21.7
DOI: 10.4238/2011.October.21.7
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Citations : 56184
Genetics and Molecular Research received 56184 citations as per google scholar report
