Y. Zhang
Isolation and characterization of polymorphic microsatellite markers for the chub mackerel (Scomber japonicus) and cross-species amplification in the blue mackerel (S. australasicus)
In this study, 10 polymorphic microsatellite markers were developed in Scomber japonicus and were examined on 30 individuals collected from the North Pacific. The number of alleles per locus ranged from 4 to 17. The observed and expected heterozygosities per locus ranged from 0.2759 to 0.8621 and from 0.43071 to 0.9177, respectively. The polymorphism information con.. Read More»
Genet. Mol. Res. 16(3): gmr16039712
DOI: 10.4238/gmr16039712
miR-1 association with cell proliferation inhibition and apoptosis in vestibular schwannoma by targeting VEGFA
A growing body of research has demonstrated the tumor suppressive function of microRNA (miR)-1 in many cancers. Our study aimed to investigate its role in vestibular schwannoma (VS). We examined miR-1 expression in 95 VS specimens and 79 normal vestibular nerves using quantitative real-time polymerase chain reaction. Moreover, miR-1 mimics, miR-1 inhibitors, and neg.. Read More»
Genet. Mol. Res. 15(4): gmr15048923
DOI: 10.4238/gmr15048923
Effect of Jianpi Bushen prescription on the expression of SHP-1 and apoptosis-related genes in chemically damaged model mice
We investigated the effect of Jianpi Bushen prescription (JBP) on the expression of the SHP-1 and apoptosis-related genes in chemically damaged model mice and a compound e-jiao slurry (EJS) group (positive control). Kunming mice received an abdominal injection of 100 mg/kg cyclophosphamide once a day for 3 consecutive days to induce chemical damage. The mice underwe.. Read More»
Genet. Mol. Res. 13(3): 2014.August.7.11
DOI: 10.4238/2014.August.7.11
Gene annotation and functional analysis of a newly sequenced Synechococcus strain
Synechococcus sp PCC 7336 represents a newly sequenced strain, and its genome is obviously different from that of other Synechococcus strains. In this analysis, local alignment and annotation databases were constructed and combined with various bioinformatic tools to carry out gene annotation and functional analysis of this strain. From this analysis, we identified .. Read More»
Genet. Mol. Res. 14(4): 2015.October.16.8
DOI: 10.4238/2015.October.16.8
Polymorphic microsatellite loci developed from the Hong Kong oyster (Crassostrea hongkongensis)
Forty polymorphic microsatellite loci were developed from Crassostrea hongkongensis using an enriched partial genomic library with magnetic beads. The polymorphism of these loci was assessed in 30 individuals from a wild population. The allele number of the polymorphic markers ranged from 2 to 13, with an average of 5.8 per locus. The polymorphism information conten.. Read More»
Genet. Mol. Res. 15(4): gmr.15048676
DOI: 10.4238/gmr.15048676
MKL1-184C>T gene polymorphism is associated with coronary artery diseasein the Chinese Han population
We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distribution of MKL1-184C>T gene polymorph.. Read More»
Genet. Mol. Res. 13(1): 2014.January.28.4
DOI: 10.4238/2014.January.28.4
Effect of atorvastatin on left atrial function of patients with paroxysmal atrial fibrillation
The aim of this study was to evaluate the effects of atorvastatin on left atrial (LA) function in paroxysmal atrial fibrillation patients. Fifty-eight paroxysmal atrial fibrillation patients were divided into two groups (treatment and control groups). The echocardiography parameters, including LA active emptying volume (LAAEV), LA active emptying fraction, LA maximum volume, LA total emptying v.. Read More»
Genet. Mol. Res. 12(3): 2013.September.10.5
DOI: 10.4238/2013.September.10.5
Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea
Recent data have indicated that inflammation may have an important correlation with obstructive sleep apnea (OSA). Studies have indicated a relationship between OSA and TNF-α gene polymorphisms. Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs. However, ZFP36 gene polymorphisms have not been investigated in OSA. Therefore, we conducted the present case-control study to assess wh.. Read More»
Genet. Mol. Res. 14(2): 2015.June.18.17
DOI: 10.4238/2015.June.18.17
Identification of smut-responsive genes in sugarcane using cDNA-SRAP
Sugarcane smut, caused by the fungus Sporisorium scitamineum, is one of the main diseases that affect sugarcane worldwide. In the present study, the cDNA-SRAP technique was used to identify genes that are likely to be involved in the response of sugarcane to S. scitamineum infection. In total, 21 bands with significant differential expression during cDNA-SRAP analysis were cloned and sequenced... Read More»
Genet. Mol. Res. 14(2): 2015.June.18.23
DOI: 10.4238/2015.June.18.23
Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression
Propofol is an extensively used intravenous anesthetic agent. The aim of the present study was to evaluate the effects of propofol on the behavior of human gastric cancer cells and the molecular mechanisms associated with this activity. The effects of propofol on proliferation and apoptosis in the SGC-7901 gastric cancer cell line were detected by an MTT assay and m.. Read More»
Genet. Mol. Res. 15(2): gmr.15027078
DOI: 10.4238/gmr.15027078
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