The mRNA expression of cell adhesion molecule 1 (CADM1) and its clinicopathological significance in esophageal squamous cell carcinoma (ESCC) tissues were investigated. CADM1 mRNA and protein expression were detected in tissue samples from 50 patients with ESCC by reverse transcription-polymerase chain reaction (RT-PCR) and streptavidin-peroxidase (SP) immunohistoch.. Read More»
Genet. Mol. Res. 16(2): gmr16029178
DOI: 10.4238/gmr16029178
We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distribution of MKL1-184C>T gene polymorph.. Read More»
Genet. Mol. Res. 13(1): 2014.January.28.4
DOI: 10.4238/2014.January.28.4
Salt stress is becoming one of the major problems in global agriculture with the onset of global warming, an increasing scarcity of fresh water, and improper land irrigation and fertilization practices, which leads to reduction of crop output and even causes crop death. To speed up the exploitation of saline land, it is a good choice to grow plants with a high level.. Read More»
Genet. Mol. Res. 13(2): http://dx.doi.org/2014.May.13.1
DOI: http://dx.doi.org/10.4238/2014.May.13.1
We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 rs13181 and rs1799793, ERCC4 rs1800067, and ERCC5 rs17655 gene polymorphisms were assessed by pol.. Read More»
Genet. Mol. Res. 14(3): http://dx.doi.org/2015.September.28.17
DOI: http://dx.doi.org/10.4238/2015.September.28.17
Increasing evidence has demonstrated that a transcription factor 7-like 2 (TCF7L2) polymorphism (rs7903146) is significantly associated with type 2 diabetes mellitus (T2DM); however, limited sample size and variance of ethnicity in the studies investigating this association have led to conflicting reports regarding its role. Therefore, a comprehensive meta-analysis was conducted to quantitative.. Read More»
Genet. Mol. Res. 15(3): gmr.15037969
DOI: 10.4238/gmr.15037969
Recently genome-wide association studies on East Asian populations reported an association between diabetes and several single nucleotide polymorphisms (SNPs) in a 40-kb linkage disequilibrium block in intron 15 of KCNQ1. However, the association between KCNQ1 variants and type 2 diabetes mellitus (T2DM) in Chinese Kazakh populations is unknown. We investigated the .. Read More»
Genet. Mol. Res. 15(2): gmr.15027503
DOI: 10.4238/gmr.15027503
Castanopsis hystrix is one of the most important and dominant species in evergreen broad-leaved forests in subtropical China. However, the population of this species undergone severe decline because of deforestation over the past 2 decades. For both conservation and forestry management, it is essential to develop molecular markers for C. hystrix. We identified 11 microsatellite loci in 2 wild p.. Read More»
Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.30.1
DOI: http://dx.doi.org/10.4238/2015.March.30.1
We constructed a Mycobacterium tuberculosis vector expressing CFP-10 and Rv2626c to examine the expression of these proteins in Escherichia coli as well as their immunoreactivity. The CFP-10 and Rv2626c genes were amplified from tuberculosis H37Rv genomic DNA using polymerase chain reaction. They were ligated into the expression vector PET30a and e.. Read More»
Genet. Mol. Res. 13(3): 2014.September.12.5
DOI: 10.4238/2014.September.12.5
In this study, meat quality traits were compared between Chinese lard- and European lean-type pigs. The association between expression of four genes (ADSL, GARS-AIRS-GART, DGAT1, and DECR1) and meat quality traits was also investigated. Meat quality traits were found to differ significantly between pig breeds. Meat color parameter values (a* and b*.. Read More»
Genet. Mol. Res. 14(4): 2015.November.18.47
DOI: 10.4238/2015.November.18.47
We examined disintegrin and metalloproteinase 17 (ADAM17) protein expression in esophageal squamous cell carcinoma and its clinical and pathological correlated factors. Western blotting and immunohistochemistry were used to detect ADAM17 protein expression in esophageal squamous cell carcinoma and the corresponding normal esophageal mucosa in 50 cases. ADAM17 protein expression in 50 cases with.. Read More»
Genet. Mol. Res. 14(2): 2015.April.30.12
DOI: 10.4238/2015.April.30.12
Genetics and Molecular Research received 56184 citations as per google scholar report