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Y. Zhu

Publications of : Y. Zhu
Cytogenomics   Research Article

CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue

The mRNA expression of cell adhesion molecule 1 (CADM1) and its clinicopathological significance in esophageal squamous cell carcinoma (ESCC) tissues were investigated. CADM1 mRNA and protein expression were detected in tissue samples from 50 patients with ESCC by reverse transcription-polymerase chain reaction (RT-PCR) and streptavidin-peroxidase (SP) immunohistoch.. Read More»

Genet. Mol. Res. 16(2): gmr16029178

DOI: 10.4238/gmr16029178

Human Genetics   Research Article

MKL1-184C>T gene polymorphism is associated with coronary artery diseasein the Chinese Han population

    Y. Xu B. Li, Y.-Z. Bao, X.-Y. Zhang, Z.-Y. Zhu, X.-F. Zhao,Y.-N. Shi, D. Li, S.-H. Chen, Y. Guo and C.-H. Cui

We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distribution of MKL1-184C>T gene polymorph.. Read More»

Genet. Mol. Res. 13(1): 2014.January.28.4

DOI: 10.4238/2014.January.28.4

Plant Genetics   Research Article

Development of EST-SSR markers related to salt tolerance and their application in genetic diversity and evolution analysis in Gossypium

    B.H. Wang, P. Zhu, Y.L. Yuan, C.B. Wang, C.M. Yu, H.H. Zhang, X.Y. Zhu, W. Wang, C.B. Yao, Z.M. Zhuang and P. Li

Salt stress is becoming one of the major problems in global agriculture with the onset of global warming, an increasing scarcity of fresh water, and improper land irrigation and fertilization practices, which leads to reduction of crop output and even causes crop death. To speed up the exploitation of saline land, it is a good choice to grow plants with a high level.. Read More»

Genet. Mol. Res. 13(2): http://dx.doi.org/2014.May.13.1

DOI: http://dx.doi.org/10.4238/2014.May.13.1

Medical Genetics   Research Article

Genetic variability of genes involved in DNA repair influence treatment outcome in osteosarcoma

    M.J. Wang, Y. Zhu, X.J. Guo and Z.Z. Tian

We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 rs13181 and rs1799793, ERCC4 rs1800067, and ERCC5 rs17655 gene polymorphisms were assessed by pol.. Read More»

Genet. Mol. Res. 14(3): http://dx.doi.org/2015.September.28.17

DOI: http://dx.doi.org/10.4238/2015.September.28.17

Human Genetics   Research Article

Correlation of the TCF7L2 (rs7903146) polymorphism with an enhanced risk of type 2 diabetes mellitus: a meta-analysis

    Y. Guan, L.H. Yan, X.Y. Liu, X.Y. Zhu, S.Z. Wang and L.M. Chen

Increasing evidence has demonstrated that a transcription factor 7-like 2 (TCF7L2) polymorphism (rs7903146) is significantly associated with type 2 diabetes mellitus (T2DM); however, limited sample size and variance of ethnicity in the studies investigating this association have led to conflicting reports regarding its role. Therefore, a comprehensive meta-analysis was conducted to quantitative.. Read More»

Genet. Mol. Res. 15(3): gmr.15037969

DOI: 10.4238/gmr.15037969

Human Genetics   Research Article

Relationship between the polymorphisms in KCNQ1 and type 2 diabetes in Chinese Kazakh population

    L.J. Cui, X.Y. Chang, L.Y. Zhu, G. Feng, T. Zhou, C.X. Zhang, K.Y. Chong and K. Sun

Recently genome-wide association studies on East Asian populations reported an association between diabetes and several single nucleotide polymorphisms (SNPs) in a 40-kb linkage disequilibrium block in intron 15 of KCNQ1. However, the association between KCNQ1 variants and type 2 diabetes mellitus (T2DM) in Chinese Kazakh populations is unknown. We investigated the .. Read More»

Genet. Mol. Res. 15(2): gmr.15027503

DOI: 10.4238/gmr.15027503

Plant Genetics   Research Article

Development and characterization of polymorphic microsatellite markers for Castanopsis hystrix (Fagaceae)

    Y. Jiang, Z.H. Li, J.Y. Zhu and H.L. Liu

Castanopsis hystrix is one of the most important and dominant species in evergreen broad-leaved forests in subtropical China. However, the population of this species undergone severe decline because of deforestation over the past 2 decades. For both conservation and forestry management, it is essential to develop molecular markers for C. hystrix. We identified 11 microsatellite loci in 2 wild p.. Read More»

Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.30.1

DOI: http://dx.doi.org/10.4238/2015.March.30.1

Microbial Genetics   Research Article

Expression and serological diagnosis of Mycobacterium tuberculosis CFP-10 and Rv2626c proteins

    Z.Y. Zhu, D. Zhang, H.B. Wang, J.Z. Xiao, Y.F. Qiu, L. Yan, D. Chen, A.G. Liu and X. Yang

We constructed a Mycobacterium tuberculosis vector expressing CFP-10 and Rv2626c to examine the expression of these proteins in Escherichia coli as well as their immunoreactivity. The CFP-10 and Rv2626c genes were amplified from tuberculosis H37Rv genomic DNA using polymerase chain reaction. They were ligated into the expression vector PET30a and e.. Read More»

Genet. Mol. Res. 13(3): 2014.September.12.5

DOI: 10.4238/2014.September.12.5

Animal Genetics   Research Article

Association between ADSL, GARS-AIRS-GART, DGAT1, and DECR1 expression levels and pork meat quality traits

    X.D. Zhang, S.J. Zhang, Y.Y. Ding, Y.F. Feng, H.Y. Zhu, L. Huang, T. Wu, J. Zhou and Z.J. Yin

In this study, meat quality traits were compared between Chinese lard- and European lean-type pigs. The association between expression of four genes (ADSL, GARS-AIRS-GART, DGAT1, and DECR1) and meat quality traits was also investigated. Meat quality traits were found to differ significantly between pig breeds. Meat color parameter values (a* and b*.. Read More»

Genet. Mol. Res. 14(4): 2015.November.18.47

DOI: 10.4238/2015.November.18.47

Medical Genetics   Research Article

Expression and clinical significance of ADAM17 protein in esophageal squamous cell carcinoma

    H.B. Liu, Y. Zhu, Q.C. Yang, Y. Shen, X.J. Zhang and H. Chen

We examined disintegrin and metalloproteinase 17 (ADAM17) protein expression in esophageal squamous cell carcinoma and its clinical and pathological correlated factors. Western blotting and immunohistochemistry were used to detect ADAM17 protein expression in esophageal squamous cell carcinoma and the corresponding normal esophageal mucosa in 50 cases. ADAM17 protein expression in 50 cases with.. Read More»

Genet. Mol. Res. 14(2): 2015.April.30.12

DOI: 10.4238/2015.April.30.12