Y.B. Zhang
miR-367 promotes uveal melanoma cell proliferation and migration by regulating PTEN
We aimed to investigate the biological role of miR-367 in uveal melanoma cell growth and migration, and the underlying mechanism responsible. Quantitative real-time polymerase chain reaction was performed to evaluate miR-367 expression in uveal melanoma tissue samples and cell lines. A miR-367 mimic, miR-367 inhibitor, and negative control oligonucleotide were trans.. Read More»
Genet. Mol. Res. 16(3): gmr16039067
DOI: 10.4238/gmr16039067
Porcine MAP3K5 analysis: molecular cloning, characterization, tissue expression pattern, and copy number variations associated with residual feed intake
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is essential for apoptosis, proliferation, differentiation, and immune responses, and is a candidate marker for residual feed intake (RFI) in pig. We cloned the full-length cDNA sequence of porcine MAP3K5 by rapid-amplification of cDNA ends. The 5451-bp gene contains a 5'-untranslated region (UTR) (718 bp), a coding region (3738 bp), and.. Read More»
Genet. Mol. Res. 15(3): gmr.15037998
DOI: 10.4238/gmr.15037998
Thermotherapy-induced reduction in glioma invasiveness is mediated by tumor necrosis factor-alpha
Thermotherapy has been proven to be effective for the treatment of various tumors, including glioma. We determined whether tumor necrosis factor-alpha (TNF-α) is involved in the regulation of the biological processes of glioma development. Reverse transcription-polymerase chain reaction (RT-PCR) and immunocytochemistry were used to investigate the levels of TN.. Read More»
Genet. Mol. Res. 14(4): 2015.October.2.11
DOI: 10.4238/2015.October.2.11
Genetic diversity of the Chinese traditional herb Blumea balsamifera (Asteraceae) based on AFLP markers
Blumea balsamifera is a commercially important medicinal herb in China and other parts of Asia. It is used to produce borneol. This plant grows in the wild, but resources have diminished greatly in recent years. We examined the genetic diversity of this species to help develop conservation strategies; 35 plants from five provinces were analyzed using AFLPs. Eight AF.. Read More»
Genet. Mol. Res. 13(2): 2014.April.14.1
DOI: 10.4238/2014.April.14.1
mRNA and protein expression levels of four candidate genes for ear size in Erhualian and Large White pigs
Porcine ear size is an important characteristic for distinguishing among pig breeds. In a previous genome-wide association study of porcine ear size, LEM domain-containing 3 (LEMD3), methionine sulfoxide reductase B3 (MSRB3), high mobility group AT-hook 2 (HMGA2), and Wnt inhibitory factor 1 (WIF1) were implicated as important candidate genes for ear size. This stud.. Read More»
Genet. Mol. Res. 16(2): gmr16029252
DOI: 10.4238/gmr16029252
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