Y.H. Cao

Publications of : Y.H. Cao

Human Genetics Research Article

Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer

Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function and protein expression. We examined the .. Read More»

Genet. Mol. Res. 16(3): gmr16038826

DOI: 10.4238/gmr16038826

Human Genetics Research Article

A microRNA-152 that targets the phosphatase and tensin homolog to inhibit low oxygen induced-apoptosis in human brain microvascular endothelial cells

Y.H. Cao, D.G. Li, B. Xu1 M.Q. Wang, N. Zhen, L.X. Man,Y.Y. Zhang1 and M. Chi

Brain damage caused by perinatal asphyxia is dangerous for neonatal infants, but the mechanism by which it occurs remains elusive. In this study, microRNA-152 (miR-152) expression was induced by low oxygen levels in rat models of hypoxia brain damage, as well as in human brain microvascular endothelial cells (HBMECs) cultured in vitro. Analysis of the sequence of mi.. Read More»

Genet. Mol. Res. 15(2): gmr.15027371

DOI: 10.4238/gmr.15027371

Human Genetics Research Article

Prognostic role of microRNA-100 in patients with bladder cancer

Y.H. Cao, H.H. Zhang,H.F. Xu, Y.J. Duan, Q. Li, B. Huang

We investigated the clinical significance and prognostic value of microRNA-100 (miR-100) in bladder cancer. Quantitative real-time polymerase chain reaction was used to analyze the expression of miR-100 in 92 pairs of human bladder cancer and adjacent normal tissue samples. Overall survival (OS) curves were plotted using the Kaplan-Meier method and were evaluated fo.. Read More»

Genet. Mol. Res. 14(4): 2015.December.7.6

DOI: 10.4238/2015.December.7.6