Y.H. Zhang
Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells
MiR-200b, a member of the microRNA-200 family, has been identified to be capable of suppressing glioma cell growth through targeting CREB1 or CD133. However, whether miR-200b affects the biological behavior (proliferation, invasion, and migration) of glioma cells is poorly understood. The aim of this study was to evaluate the effect of miR-200b on the biological beh.. Read More»
Genet. Mol. Res. 16(1): gmr16019281
DOI: 10.4238/gmr16019281
Expression of OPG, RANKL, and RUNX2 in rabbit periodontium under orthodontic force
This study aims to investigate the expression changes of RANKL, RUNX2, and OPG in rabbit periodontal tissues under orthodontic force and explore its effect on the remodeling of periodontal tissues. A total of 16 specific pathogen-free rabbits were used in this study. The maxillary appliance was worn on the right (experimental) side, and the appliance-free left side was used as the control. Rabb.. Read More»
Genet. Mol. Res. 14(4): 2015.December.29.48
DOI: 10.4238/2015.December.29.48
Characterization of microRNAs from goat (Capra hircus) by Solexa deep-sequencing technology
MicroRNAs (miRNAs) are an important class of small noncoding RNAs that are highly conserved in plants and animals. Many miRNAs are known to mediate a myriad of cell processes, including proliferation and differentiation, via the regulation of some transcription and signaling factors, which are closely related to muscle development and disease. In this study, small RNA cDNA libraries of Boer goa.. Read More»
Genet. Mol. Res. 12(2): 2013.June.13.4
DOI: 10.4238/2013.June.13.4
miR-124 radiosensitizes human esophageal cancer cell TE-1 by targeting CDK4
Radiotherapy is one of the most important treatments for esophageal cancer, but radioresistance remains a major challenge. Previous studies have shown that microRNAs (miRNAs or miRs) are involved in human cancers. miR-124 has been widely reported in various cancers and it is intimately involved in proliferation, cell cycle regulation, apoptosis, migration, and invas.. Read More»
Genet. Mol. Res. 15(2): gmr.15027893
DOI: 10.4238/gmr.15027893
DNA methylation involved in proline accumulation in response to osmotic stress in rice (Oryza sativa)
Proline accumulation is involved in plant osmotic stress tolerance. Given that DNA methylation is related to almost all metabolic processes through regulation of gene expression, we suspected that this epigenetic modification and proline biosynthesis are probably related. To test this, we investigated whether osmotic stress-induced proline accumulation is associated with DNA methylation modifi .. Read More»
Genet. Mol. Res. 12(2): 2013.April.17.5
DOI: 10.4238/2013.April.17.5
Association of T1740C polymorphism of L-FABP with meat quality traits in Junmu No. 1 white swine
This study was designed to investigate a single nucleotide polymorphism in intron 1 of the liver fatty acid-binding protein (L-FABP) gene in 156 Junmu No. 1 white swine using PCR-single-strand conformational polymorphism. The association between the polymorphism and meat quality traits was also studied. The cloning and sequencing results indicated that the polymorphism in intron 1 was due to a .. Read More»
Genet. Mol. Res. 12(1): 2013.January.30.9
DOI: 10.4238/2013.January.30.9
Analysis of the relationship between ribosomal DNA ITS sequences and active components in Rhodiola plants
Rhodiola plants are a valuable resource in traditional Chinese medicine. The objective of this study was to evaluate the correlation between ribosomal DNA internal transcribed spacer (ITS) sequences and the three active components in Rhodiola plants. For this, we determined ITS sequence polymorphisms and the concentrations of active components salidroside, tyrosol, .. Read More»
Genet. Mol. Res. 15(4): gmr15049337
DOI: 10.4238/gmr15049337
Correlation between polymorphism of platelet alloantigen genes HPA-1-5 and type 2 diabetes complication by carotid atherosclerosis in a Chinese population
We investigated the association between the polymorphism of human platelet alloantigen genes HPA-1-HPA-5 and the complication of type 2 diabetes mellitus (T2DM) by carotid atherosclerosis (CA) among Han people in Guiyang District, China. Ninety-nine T2DM patients were selected from the Affiliated Hospital of Guiyang Medical College and divided into a CA(+) group and a CA(-) group. A control gro.. Read More»
Genet. Mol. Res. 14(2): 2015.May.4.19
DOI: 10.4238/2015.May.4.19
Detection of differentially expressed genes in the longissimus dorsi of Northeastern Indigenous and Large White pigs
Recent attention in pig breeding programs has focused on the improvement of pork quality in response to increasing consumer demands. Compared to the fatty-type Northeastern Indigenous (Chinese) breed of pigs, the lean-type Large White has lower intramuscular fat and inferior eating quality from the perspective of the Chinese consumer. In order to investigate the mol.. Read More»
Genet. Mol. Res. 10(2):
Influence of thoracic duct ligation on the lipid metabolism of patients with esophageal carcinoma after esophagectomy
The aim of this study was to determine the influence of thoracic duct ligation on the lipid metabolism of patients with esophageal carcinoma after esophagectomy. A total of 74 patients with esophageal carcinoma who underwent esophagectomy were divided into 2 groups according to whether or not their thoracic duct was ligated. Thirty-nine patients were in the thoracic duct ligation group and the .. Read More»
Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.30.11
DOI: http://dx.doi.org/10.4238/2015.March.30.11
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Citations : 56184
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