Y.Q. Wang
Suppression of the biological activity of neuroglioma cells by down-regulation of miR-1
Neuroglioma is associated with high rates of malignancy, metastasis, and recurrence. Recently, research on the roles of microRNAs (miR) in cancer prognosis has formed an important area of research as differential expression of miRNAs has been observed in different cancers. However, the detailed mechanism by which miRNAs regulate glioma remains unknown. Thus, we inve.. Read More»
Genet. Mol. Res. 16(3): gmr16039256
DOI: 10.4238/gmr16039256
Aldehyde dehydrogenase 2 (ALDH2) polymorphism gene and coronary artery disease risk: a meta-analysis
We studied the association between aldehyde dehydrogenase 2 (ALDH2) polymorphism and coronary artery disease (CAD) and clarified the mechanisms underlying this association. We searched the ISI, Medline (Ovid), PubMed, CNKI, Wanfang, and Weipu Databases. Statistical analysis was performed using Revman 5.0 and Stata12.0 softwares. A total of 3305 cases and 5016 controls in 12 case-control studies.. Read More»
Genet. Mol. Res. 14(4): 2015.December.23.38
DOI: 10.4238/2015.December.23.38
Construction of a primary DNA fingerprint database for cotton cultivars
Forty core primers were used to construct a DNA fingerprint database of 132 cotton species based on multiplex fluorescence detection technology. A high first successful ratio of 99.04% was demonstrated with tetraplex polymerase chain reaction. Forty primer pairs amplified a total of 262 genotypes among 132 species, with an average of 6.55 per primer and values of polymorphism information conten.. Read More»
Genet. Mol. Res. 12(2): 2013.January.30.3
DOI: 10.4238/2013.January.30.3
Effects of different anesthetic approaches on postoperative complications in HIV-infected patients
The aim of this study was to investigate the effects of three different methods of anesthesia on patients with human immunodeficiency virus (HIV) infection, which could lead to an improvement in postoperative outcomes in these patients. A total of 90 patients undergoing an operation while being treated for an HIV infection were included in this study. Patients were divided into three groups (N .. Read More»
Genet. Mol. Res. 14(3): 2015.August.7.22
DOI: 10.4238/2015.August.7.22
Initial periodontal therapy for the treatment of gingival pregnancy tumor
The purpose of this study was to evaluate the clinical efficacy of initial periodontal therapy in gingival pregnancy tumors. Thirty-nine patients diagnosed with gingival tumors of pregnancy between 2007 and 2015 were enrolled in this study. The patients received initial periodontal therapy, then supportive periodontal therapies at 3- to 6-month intervals. The patien.. Read More»
Genet. Mol. Res. 15(2): gmr.15028119
DOI: 10.4238/gmr.15028119
Effect of compound Maqin decoction on TGF-�²1/Smad proteins and IL-10 and IL-17 content in lung tissue of asthmatic rats
In this research, compound Maqin decoction (CMD) has been shown to positively affect in airway inflammation of asthma models. We evaluated the effects of CMD on the expression of transforming growth factor (TGF)-β1/Smad proteins, interleukin (IL)-17, and IL-10 in lung tissue of asthmatic rats. Asthma was induced in a rat model using ovalbumin. After a 4-week tr.. Read More»
Genet. Mol. Res. 15(3): gmr.15037539
DOI: 10.4238/gmr.15037539
FSHR gene Thr307Ala and Asn680Ser polymorphisms in infertile men: an association study in North China and meta-analysis
Male infertility is a complex multifactorial and polygenic disease, and genetic factors play an important role in its formation and development. Recently, the association between follicle stimulating hormone receptor (FSHR) gene polymorphisms and male infertility risk has attracted widespread attention due to the unique biological functions of FSH. The aim of this study was to further explore t.. Read More»
Genet. Mol. Res. 14(2): 2015.May.25.11
DOI: 10.4238/2015.May.25.11
Influence of hepatic ischemia-reperfusion on postoperative spatial cognitive function in mice
The aim of this study was to investigate the effects of partial hepatic ischemia/reperfusion (I/R) on postoperative cognitive function in mice. One hundred Kunming mice were randomized into control group (N = 20), sham group (N = 20) and I/R group (N = 60), which was equally divided into 3 subgroups according to the ischemia time (20, 30 and 40 min). Half of the mic.. Read More»
Genet. Mol. Res. 13(3): 2014.July.29.4
DOI: 10.4238/2014.July.29.4
Estrogenic effects of flavonoid components in Xiaoyao powder
The objective of this study was to evaluate the estrogenic effects and mechanisms of three flavonoid components in Xiaoyao powder: quercetin, kaempferol, and isorhamnetin. The drugs were used to treat estrogen receptor (ER)-positive human breast cancer MCF-7 cells, and proliferation was measured using the MTT method. The expression of proteins and mRNA of the ER subtype were measured using west.. Read More»
Genet. Mol. Res. 15(1): gmr.15017500
DOI: 10.4238/gmr.15017500
Expression profiles of variation integration genes in bladder urothelial carcinoma
Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to construct a causal-target module network.. Read More»
Genet. Mol. Res. 13(2): http://dx.doi.org/2014.April.30.9
DOI: http://dx.doi.org/10.4238/2014.April.30.9
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