Y.X. Yang

Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells

• C. Zhao
• Z.G. Ma
• S.L. Mou
• Y.X. Yang
• Y.H. Zhang
• W.C. Yao

MiR-200b, a member of the microRNA-200 family, has been identified to be capable of suppressing glioma cell growth through targeting CREB1 or CD133. However, whether miR-200b affects the biological behavior (proliferation, invasion, and migration) of glioma cells is poorly understood. The aim of this study was to evaluate the effect of miR-200b on the biological beh.. Read More»

Genet. Mol. Res. 16(1): gmr16019281

DOI: 10.4238/gmr16019281

Lack of association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population

J.J. Lu, H.Q. Zhang, P. Mai, X. Ma, X. Chen, Y.X. Yang and L.P. Zhang

We conducted a case-control study to assess the association between single nucleotide polymorphisms in the ERCC5 promoter (rs2094258 and rs751402) and development of gastric cancer in a Chinese population. This investigation included 184 patients with pathologically diagnosed gastric cancer and 206 healthy subjects recruited between October 2012 and December 2014. T.. Read More»

Genet. Mol. Res. 15(2): gmr.15027779

DOI: 10.4238/gmr.15027779

Stimulation of bacterial biofilms on Th17 immune cells

G.Q. Wang, L. Wang, H.L. Zhang, Y.Q. Dong and Y.X. Yang

We investigated the role of bacterial biofilms in stimulating T helper 17 (Th17) cells in infected organisms. The formation of bacterial biofilms isolated from clinical lavage fluid samples was measured. Th17 cells and interleukin 17 (IL-17) levels in the peripheral blood of healthy individuals, people infected by biofilm bacteria, people infected by non-biofilm bacteria, and in the lavage flui.. Read More»

Genet. Mol. Res. 14(3): 2015.July.13.18

DOI: 10.4238/2015.July.13.18

Differential expression of peroxisome proliferator-activated receptor �³, fatty acid synthase, and hormone-sensitive lipase in fat-tailed and thin-tailed sheep breeds

X.C. Xu,B.B. Li,X. Wei,Y.X. Yang,X.L. Wang,Y.L. Chen

Tail fat content affects meat quality, and it varies in different sheep breeds. Theoretically, lipid metabolism contributes to variation in tail fat content. Tail length, tail width, and tail girth were measured in live Tong sheep (with both short fat tail and long fat tail), Shaanbei fine wool sheep (long thin tail), Tan sheep (short fat tail), Kazakh sheep (hip fa.. Read More»

Genet. Mol. Res. 14(4): 2015.December.1.14

DOI: 10.4238/2015.December.1.14

Differential expression of peroxisome proliferator-activated receptor �³, fatty acid synthase, and hormone-sensitive lipase in fat-tailed and thin-tailed sheep breeds

X.C. Xu, B.B. Li, X. Wei, Y.X. Yang, X.L. Wang, Y.L. Chen

Tail fat content affects meat quality, and it varies in different sheep breeds. Theoretically, lipid metabolism contributes to variation in tail fat content. Tail length, tail width, and tail girth were measured in live Tong sheep (with both short fat tail and long fat tail), Shaanbei fine wool sheep (long thin tail), Tan sheep (short fat tail), Kazakh sheep (hip fa.. Read More»

Genet. Mol. Res. 14(4):

A novel 3-base pair deletion of the CRYAA gene identified in a large Chinese pedigree featuring autosomal dominant congenital perinuclear cataract

X.D. Kong, N. Liu, H.R. Shi, J.M. Dong, Z.H. Zhao, J. Liu,J. Li-Ling and Y.X. Yang

Congenital cataract is caused by reduced transparency of the lens resulting from metabolic disorders during the fetal period. The disease shows great heterogeneity both clinically and genetically. We identified a 4-generation ethnic Han Chinese family affected by autosomal dominant congenital perinuclear cataract. The patients underwent full clinical and ophthalmologic examinations to rule out .. Read More»

Genet. Mol. Res. 14(1): 2015.January.23.16

DOI: 10.4238/2015.January.23.16