Z.H. Fu
Phenotypic classification of gastric signet ring cell carcinoma and its relationship with K-ras mutation
We aimed to analyze gastric signet ring cell (SRC) carcinoma subtypes by investigating gastric and intestinal phenotypic marker expression, and explore the relationship between phenotype and K-ras mutation. Immunohistochemistry was performed on 163 SRC carcinoma patient specimens to detect gastric (MUC1, MUC5AC, and MUC6) and intestinal (MUC2 and CDX2) phenotypic ma.. Read More»
Genet. Mol. Res. 16(2): gmr16029181
DOI: 10.4238/gmr16029181
Influence of interleukin-18 gene polymorphisms on acute pancreatitis susceptibility in a Chinese population
We investigate the relationship between IL-18 -607C/A and -137G/C genetic polymorphisms and development of acute pancreatitis in a Chinese population. A total of 153 patients were consecutively recruited from the First Affiliated Hospital of Chongqing Medical University between January 2013 and November 2014. Genotyping of IL-18 -607C/A and -137G/C variants was perf.. Read More»
Genet. Mol. Res. 15(3): gmr.15038394
DOI: 10.4238/gmr.15038394
IFGFA: Identification of featured genes from genomic data using factor analysis
In this study, a software tool (IFGFA) for identification of featured genes from gene expression data based on latent factor analysis was developed. Despite the availability of computational methods and statistical models appropriate for analyzing special genomic data, IFGFA provides a platform for predicting colon cancer-related genes and can be applied to other cancer types. The computational.. Read More»
Genet. Mol. Res. 15(3): gmr.15038803
DOI: 10.4238/gmr.15038803
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