Z.M. Li
Improvement in orthopedic outcome score and reduction in IL-1�², CXCL13, and TNF-�± in synovial fluid of osteoarthritis patients following arthroscopic knee surgery
Knee osteoarthritis (KOA) is a common degenerative joint disease and immune system dysregulation has been implicated in its pathogenesis. The effect of arthroscopic knee surgery, an important method for KOA diagnosis and treatment, on the expression of immune regulators remains poorly understood. We aimed to investigate the clinical efficacy of such surgery and its .. Read More»
Genet. Mol. Res. 16(3): gmr16039487
DOI: 10.4238/gmr16039487
MicroRNA screening and functional study of obliterative bronchiolitis in a rat model simulating lung transplantation
The aim of this study was to provide the experimental basis for effective prevention and treatment of obliterative bronchiolitis (OB) by studying the changes on the microRNA (miRNA) expression profile after an orthotopic tracheal transplantation (OTT) simulating lung transplantation (LT). The OTT was performed on inbred rats to establish an OB animal model simulating LT, which was confirmed suc.. Read More»
Genet. Mol. Res. 14(4): 2015.December.29.40
DOI: 10.4238/2015.December.29.40
Genetic relationship between lodging and lodging components in barley (Hordeum vulgare) based on unconditional and conditional quantitative trait locus analyses
Lodging (LD) is a major constraint limiting the yield and forage quality of barley. Detailed analyses of LD component (LDC) traits were conducted using 246 F2 plants generated from a cross between cultivars ZQ320 and 1277. Genetic relationships between LD and LDC were evaluated by unconditional and conditional quantitative trait locus (QTL) mapping with 117 simple s.. Read More»
Genet. Mol. Res. 13(1): http://dx.doi.org/2014.March.17.19
DOI: http://dx.doi.org/10.4238/2014.March.17.19
In silico analysis of gene content in tomato genomic regions mapped to the Ty-2 resistance gene
Tomato yellow leaf curl virus is one of the main diseases affecting tomato production worldwide. Previous studies have shown that Ty-2 is an important resistance gene located between molecular markers C2_At2g28250 (82.3 cM) and T0302 (89.0 cM), and exhibits strong resistance to tomato yellow leaf curl virus in Asia. In this study, Ty-2 candidate genes were subjected to bioinformatic analysis fo.. Read More»
Genet. Mol. Res. 14(3): 2015.July.17.2
DOI: 10.4238/2015.July.17.2
Assessment of the genetic diversity of tomato yellow leaf curl virus
The objective of the present study was to analyze the genetic diversity of tomato yellow leaf curl virus (TYLCV). Representative TYLCV sequences were searched in the National Center for Biotechnology Information database. Comprehensive analysis of TYLCV was performed using bioinformatics by examining gene structure, sequence alignments, phylogeny, GC content, and homology. Forty-eight represent.. Read More»
Genet. Mol. Res. 14(1): 2015.January.26.7
DOI: 10.4238/2015.January.26.7
In silico identification and characterization of the WRKY gene superfamily in pepper (Capsicum annuum L.)
The WRKY family is one of the most important transcription factor families in plants, involved in the regulation of a broad range of biological roles. The recent releases of whole-genome sequences of pepper (Capsicum annuum L.) allow us to perform a genome-wide identification and characterization of the WRKY family. In this study, 61 CaWRKY proteins were identified in the pepper genome. Based o.. Read More»
Genet. Mol. Res. 15(3): gmr.15038675
DOI: 10.4238/gmr.15038675
Gene expression profiles of the heterotrophic microalga Chlorella pyrenoidosa F-9
A strain of the microalga Chlorella pyrenoidosa F-9 in our laboratory showed special characteristics when transferred from autotrophic to heterotrophic culture. In order to elucidate the possible metabolic mechanism, the gene expression profiles of the autonomous organelles in the green alga C. pyrenoidosa under autotrophic and heterotrophic cultivation were compared by suppression subtractive .. Read More»
Genet. Mol. Res. 13(4): 2014.October.20.17
DOI: 10.4238/2014.October.20.17
Association of monocyte chemoattractant protein-1 rs1024611 and telomerase rs2736100 polymorphisms with susceptibility to pulmonary tuberculosis in Han Chinese population
Pulmonary tuberculosis (PTB) is caused by Mycobacterium tuberculosis infection and accumulated evidence reveals the genetic context of its infection phenotypes. Monocyte chemoattractant protein-1 (MCP-1) rs1024611 variant is shown to be associated with PTB susceptibility in some studies, but significant disparities exist. In addition, telomerase plays a key role in .. Read More»
Genet. Mol. Res. 16(3): gmr16039697
DOI: 10.4238/gmr16039697
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