What and why you need to know about beta thalassemia: A genetic disorder
Authors: Nitu Nigam*, S P Verma, Swati Sinha, Kirti Upadhyay, Sanjay Nigam, Vimala Venkatesh, Soniya Nityanand
Thalassemia is a genetic disorder. Now a day’s beta thalassemia is becoming quite prevalent all over the world. The prevalence rate is varied in the different state of India. Beta (β)-thalassemia is of three types. The beta thalassemia major, minor and inter-media. The beta Thalassemia major patients have to be dependent on regular blood transf.. Read More»
- Genet. Mol. Res. 23(4):
Noonan syndrome: Discovering new mutations?
Authors: Marta Guzmán Pérez*, Joaquin Gomez Garrido, Gema Giner Merino, Pablo López Sanz
We present the case of a 50-year-old white male that was brought to the emergency services due to the presence of speech disturbances and drowsiness in the past four or five days. He did not have any other symptoms apart from those but in the physical examination, some clinical characteristics were identified and could suggest the existence of a geneti.. Read More»
- Genet. Mol. Res. 23(4):
Detection of HER2 gene amplification in formalin-fixed and paraffin-embedded breast cancer tissues by quantitative real time polymerase chain reaction in ER and PR-positive HER2 immunohistochemistry 0 or ≥ 2+ breast cancer
Authors: Maisaa Al-Wohhaib*, Salah K Alwaheeb, Ghaneema Enad Al-shammari
Amplification of the human epidermal growth factor receptor 2 (HER2) genes and overexpression of its gene product, the HER2 protein was found in 20% of breast cancers. Genetic instability and hence aberrant HER2 amplification may be associated with breast cancer progression. HER2 status determination plays an important .. Read More»
- Genet. Mol. Res. 23(4):
Correlation and path coefficient analyses of Rhodes grass (Chloris gayana) genotypes at Mechara Agricultural Research Center on Station
Authors: Lensa Urgesa*, Tamirat Dinkale, Jibrail Hassen
Sympathetic the nature and degree of association between dry matter yield and dry matter yield related traits is the essential to study for any underutilized forage improvements of sustainable genetic enhancement. Though, there is a lack of sufficient evidence on dry matter yield and related trait correlation and path coefficient analysis of Rhodes grass .. Read More»
- Genet. Mol. Res. 23(4):
The ramifications of Darwin's "On the origin of species": From eugenics to modern genomics
Authors: Richard Murdoch Montgomery
This article delves into the historical development and ramifications of divergent theories that have emerged since the publication of Darwin's seminal work, "On the Origin of Species" in 1856. It traces the evolution of thought from Darwin's revolutionary ideas through the controversial era of eugenics, the groundbreaking discovery of D.. Read More»
- Genet. Mol. Res. 23(4):
Evaluation of genetic variability and association of traits in Kabuli chickpea (Cicer arietinum L.) genotypes in East Gojjam Zone, Northwestern, Ethiopia
Authors: Gebremeskel Mequanint Mulu*, Ahadu Menzir, Animaw Dessie
Genetic variability study is an important task for generating genetic information on variability and association of important traits of Kabuli chickpea for further improvement through selection and/or hybridization. In this regard, the study aimed to estimate the magnitude of genetic variation and association of traits among 36 Kabuli chickpea genotypes f.. Read More»
- Genet. Mol. Res. 23(3):
Evaluation of genetic variability in bread wheat (Triticum aestivum L.) genotypes at Holeta, Central Ethiopia
Authors: Fikir Desalew
The experiment was conducted in in alpha-lattice design at Holeta Agricultural Research Center in the 2021 main cropping season with two replications at experimental area of research farm. Analysis of variance revealed that there were statistically significant differences among the genotypes for most of their traits. The varieties showed wider variability.. Read More»
- Genet. Mol. Res. 23(3):
Ethical opinions regarding genetic engineering
Authors: Cagan E. Eren
Genetic engineering is one of the most ethically controversial scientific principles of human history. Biologists, philosophers, experts and even people that have different jobs, each have their own unique opinion on the subject. It is a known fact that public attitudes are one of the key determinants in the development of a research topic. Based on this .. Read More»
- Genet. Mol. Res. 23(2):
Nanotechnology to treat sepsis
Authors: Peng Jin-liang, Kashif Rafiq Zahid, Zhou Yu-ming*, Qurban Ali, Qiu Chong-Rong
Infectious diseases have gotten less scientific focus and funding than cancer and cardiovascular ailments. Furthermore, interdisciplinary cooperation has not traditionally been actively used to create extracorporeal devices. However, significant technical issues in the area can be resolved by interdisciplinary research involving complex fluid .. Read More»
- Genet. Mol. Res. 23(2):
Recent advances in gene pyrimiding with special reference to rice (Oryza sativa L.)
Authors: Anjali Singh
The improvement of sub-atomic hereditary qualities and related innovation like MAS has prompted the rise of another field in plant rearing quality pyramiding (IRRI).The term gene pyramiding is used in agricultural research to describe a.. Read More»
- Genet. Mol. Res. 23(2):