Genetic diversity and structure in Tunisian wild cherries and cultivated sweet cherries revealed by SSR markers
Authors: Azizi-Gannouni Thouraya, Ammari Youssef, Mnasri Rahmani Sameh, Ben Naceur M�barek, Albouchi Ali
Wild cherries are concentrated at high altitudes in northern Tunisia and cultivated sweet cherries are well adapted to low altitudes. This study aims to compare local wild and cultivated sweet cherries (Prunus avium L.) in the northern of Tunisia. To elucidate genetic variation of 21 cultivated sweet cherries (one landrace and 20 foreigner cultivars) .. Read More»
- Genet. Mol. Res. 20(6):
Co-targeting the EGFR and PI3K/Akt pathway to overcome therapeutic resistance in head and neck squamous cell carcinoma: What about autophagy?
Authors: Hannah Zaryouh, Jinthe Van Loenhout, Marc Peeters, Jan Baptist,Vermorken, Filip Lardon, An Wouters
Recent insights in the PI3K/Akt pathway as a promising therapeutic target in combination with EGFR-targeting agents to treat head and neck squamous cell carcinoma. The Epidermal Growth Factor Receptor (EGFR) is overexpressed in the majority of Head and Neck Squamous Cell Carcinomas (HNSCC). This triggered the development of multiple anti.. Read More»
- Genet. Mol. Res. 20(6):
Optogenetic approach improves neuroregenerative potential of stem cell-based therapies
Authors: Zahra-Soheila Soheili, Hoda Shams Najafabadi
Neural cells represent very limited regenerative capacity and cannot prevent the progression of central nervous system, and retinal, neurodegenerative diseases such as Alzheimer's, Parkinson's, Retinitis pigmentosa or age related macular degeneration diseases. Stem cell based regenerative strategies revealed successful preclinical transplantation outco.. Read More»
- Genet. Mol. Res. 20(6):
Mitochondrial sirtuins in cancer
Authors: Mitochondrial sirtuins in cancer
All living beings require energy and the ultimate source for this energy in eukaryotes are mitochondria – originally an organelle of bacterial origin and eventually incorporated into the cytoplasm. Mitochondrial bioenergetics and dynamics are essential for the maintenance of cellular and metabolic homeostasis and any imbalance can result in diseases.. Read More»
- Genet. Mol. Res. 20(6):
A brief study about DNA polymerase
Authors: Mohammad irani hafeez
Ribonucleases (RNases) are key players of the host immunity and contribute to maintaining tissue homeostasis and body fluid sterility. Secreted upon a diversity of cellular injuries, they mediate signaling processes, and have been classified as alarmins. Recent literature reveals how the immune response system uses common strategies to fight both cance.. Read More»
- Genet. Mol. Res. 20(6):
A brief note on chromosomal abberation
Authors: Gerome Taylor*
Reverse transcriptase, additionally called RNA-coordinated DNA polymerase, a chemical encoded from the hereditary material of retroviruses that catalyzes the record of retrovirus RNA (ribonucleic corrosive) into DNA (deoxyribonucleic corrosive).. Read More»
- Genet. Mol. Res. 20(4):
A brief study on molecular sensors
Authors: Jack Hamilton*
A sub-atomic sensor, otherwise called a chemosensor or test, is a sub-atomic or supramolecular-based framework that can change test analyte connections into a sign which permits analyte detecting... Read More»
- Genet. Mol. Res. 20(4):
DNA replication: Process in Eukaryotes
Authors: Harsh Pandey*
DNA replication, otherwise called semi-moderate replication, is the interaction by which DNA is basically multiplied. It is a significant interaction that happens inside the separating cell... Read More»
- Genet. Mol. Res. 20(4):
Lac operon: It's structure and function
Authors: Stephan Morris*
Early bits of knowledge into components of transcriptional guideline came from investigations of E. coli by scientists Francois Jacob and Jacques Monod. In E. coli, and numerous different microscopic organisms, qualities encoding a few distinct proteins might be situated on a solitary record unit called an operon. The qualities in an operon share the equi.. Read More»
- Genet. Mol. Res. 20(4):
DNA and Chromatin Fibres
Authors: Mark Jones*
Chromatin is a complex of macromolecules made out of DNA, RNA, and protein, which is found inside the center of eukaryotic cells. Chromatin exists in two constructions: heterochromatin (united) and euchromatin (extended)... Read More»
- Genet. Mol. Res. 20(4):