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Medical Genetics   Research Article

Diagnosis of Idiopathic Primary Infertility in a Consanguineous Infertile Family using Clinical and Molecular Cytogenetic Techniques

Authors: H. Muhammad, R. Khan, F. Wahab, I. Khan, B. Shah, A. Ali, N. Farooqi, Dil, N. Ali, F. Jalil and S. Ali

Background: Male infertility is a multifactorial medical problem affecting around 7% of the male population in whom 1% are affected by Non Obstructive Azoospermia (NOA). Despite of advanced diagnostic techniques, majority of the infertility cases remain idiopathic .Therefore more evidence based scientific research is required to investigate the underlying.. Read More»

Genet. Mol. Res. 19(5):
Human Genetics   Research Article

Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphisms and Risk of Aneurysmal Subarachnoid Hemorrhage: An Updated Meta-Analysis

Authors: N. Manabesh, M. Shubham, K. Amit, S. Rakhee, K. Pradeep

Previously published studies have examined whether the polymorphisms (G894T, 4b/a, and T786C) in the Endothelial Nitric Oxide Synthase (eNOS) gene are associated with risk of Aneurysmal Subarachnoid Hemorrhage (aSAH), have reported conflicting results. Thus, we performed a meta-analysis to examine the potential association between these three single nucle.. Read More»

Genet. Mol. Res. 19(5):
Human Genetics   Research Article

Environment Association in Chickpea Genotypes Utilizing AMMI And GGE Biplot Model

Authors: M.G. Azam, M.S. Iqba, M.A. Hossain and M.F. Hossain

Chickpea (Cicer arietinum L.) is generally grown-up underneath rainfed conditions inside the Barind space in Bangladesh, any place drought spell is that the principle production constraint. Genotype × Environment Interaction (GEI) was acclimated with making estimation of the grain yield and to get a handle on the G × E connection designs by an.. Read More»

Genet. Mol. Res. 19(4):
Human Genetics   Research Article

Fourier-Transform Infrared Spectroscopy, Antioxidant, Phytochemical and Antibacterial Screening of N-Hexane Extracts of Punica granatum, A Medicinal Plant

Authors: M. Sharif, F. Ansari, A. Malik, Q. Ali, Z. Hasan and N.U.H. Khan

Pomegranate is a fruit bearing plant belonging to Lythraceae; in botanic language it is called Punica granatum. It is been considered as a traditional medicine for the cure of many diseases. The purpose of this study was to investigate the antimicrobial activity and phytochemicals present qualitatively present in different parts of Pomegranate plant and t.. Read More»

Genet. Mol. Res. 19(4):
Medical Genetics   Research Article

Development and Transferability of Microsatellites Markers for Species of the Saltans Group of Drosophila (Diptera: Drosophilidae)

Authors: B.E. Roman, B.M. Trava and L. Madi-Ravazzi

The microsatellite markers (SSRs) are highly polymorphic, fast evolving, and regarded as neutral markers. Due to these traits, they have been widely used in population studies. The development of specific SSRs for a given species opens possibilities for the application, by means of transferability, in population studies of other species that are phylogene.. Read More»

Genet. Mol. Res. 19(4):
Medical Genetics   Research Article

Molecular Characterization of Tuf Gene and Antibiotic Susceptibility Patterns of Streptococcus Species in Local Population of Lahore, Pakistan

Authors: A. Mahmood, A. J. Sami and Q. Ali

Background: Multi Drug Resistance (MDR) is a global problem which is expeditiously increasing. Different antimicrobial drugs have been reported resistant against various Streptococcus species. This has been a threat to local individuals in all over the world specifically in developing countries including Pakistan. Decreased efficiency of drugs due to emer.. Read More»

Genet. Mol. Res. 19(4):
Human Genetics   Research Article

Targeted Delivery of Insulin by Psyllium Plant (Plantago ispaghula) based hydrogels/membranes

Authors: A.J. Sami, U. Ahmad, M. Karamat, M.N. Hafeez and Q. Ali

Developments in therapeutics are the need of hour for the benefit of mankind and to increase the quality of life. Diabetes mellitus is a non-curable disease affecting a great amount of world’s population. This genetic disorder gets worse with time and ultimately leads to various complications like renal failure, lower limb amputation, heart diseases.. Read More»

Genet. Mol. Res. 19(2):
Medical Genetics   Research Article

Knock down of molt regulating gene for development control of Helicoverpa armigera

Authors: M.N. Sharif, M.S. Iqbal, R. Alam, B. Tabassum, M.F. Awan, Q. Ali and I.A. Nasir

RNA interference (RNAi) caused by exogenous double-stranded RNA (dsRNA) is a powerful tool, and to date is widely adopted to knockdown genetic targets crucial for growth and development of agriculturally important insect pests. Helicoverpa armigera is a pest feeding on more than 30 economically important crops worldwide and a major threat. Resistance to i.. Read More»

Genet. Mol. Res. 19(2):
Medical Genetics   Research Article

Genetic Evaluation for Effects of Salt and Drought Stress on Growth Traits of Zea mays Seedlings

Authors: M. Khalil, M.S. Rashid, Q. Ali and A. Malik

Maize is an important grain cash crop grown throughout the world for its grain and fodder. It is highly sensitive for abiotic stress conditions; like drought, chilling, alkalinity, heat, salt and cold conditions. Present study was carried out to find out the effects of salt or NaCl and drought stress on three selected maize genotypes viz., P6103, L5971 an.. Read More»

Genet. Mol. Res. 19(3):
Human Genetics   Research Article

Evaluation of Genetic Variability in Wheat and Maize under Heavy Metal and Drought Stress

Authors: M. Tahir, M.S. Rashid, Q. Ali and A. Malik

There are certain conditions which cause a change in the growth pattern of plants. These circumstances are significantly effective in growth and cultivation of major crops. The effects of higher levels of copper sulphate through fertilizers can be effective in reducing the growth of a healthy plant. An experiment was conducted in the greenhouse of Institu.. Read More»

Genet. Mol. Res. 19(3):