Bcl2
Investigation of the role of apoptosis, necroptosis and DNA damage signaling pathways in multiple sclerosis
Authors: Romina Dastmalchi, Arezou Sayad, Mir Davood Omrani, Soudeh Ghafouri-Fard, Shahram Arsang-Jang, Mehrdokht Mazdeh, Mohammad Taheri*
Multiple sclerosis (MS) as the most common autoimmune disorder in the central nervous system is a major health problem. MS is a complex disease with multiple environmental and genetic factors participating in it. In the present study, we evaluated the expression of 3 genes named BCL2, CASP2 and CASP8 in peripheral blood of 50 MS patients and 50 healthy co.. Read More»
- Genet. Mol. Res. 17(4):
- http://dx.doi.org/gmr16039937
- DOI:
- http://dx.doi.org/10.4238/gmr16039937
Effects of BCL2 transfection on the cell cycle and proliferation of human GES-1 cells
Authors: G.Y. Shi, L.L. Zhao, K. Zhang, H.X. Zhou, A.H. Liu, J. Li, G. Li and L.H. Zhu
We investigated the effects of BCL2 transfection on the cell cycle and proliferation of GES-1 cells. A pcDNA3-BCL2 plasmid was used to transfect GES-1 cell line human gastric epithelial cells. Clones were obtained by G418 screening. BCL2-positive cells were identified by fluorescence immunohistochemistry. The pcDNA3-BCL2 vecto.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.5.15
- DOI:
- 10.4238/2015.October.5.15
Assessment of BCL2/J(H) translocation in healthy individuals exposed to low-level radiation of 137CsCl in Goi�¢nia, Goi�¡s, Brazil
Authors: H.F. Nunes A.B.A. Laranjeira J.A. Yunes E.O.A. Costa C.O. de A. Melo D. de M. e Silva A.D. da Cruz
Healthy radio-exposed individuals who received low levels of Cesium-137 radiation during the accident that occurred in GoiÃ?¢nia in 1987, their families and controls were tested for the detection of t(14;18)-rearranged B cells in peripheral blood by using a highly sensitive, real-time quantitative PCR method. The chromosomal translocation t(14;18)(q32;q21) .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.6
- DOI:
- 10.4238/2013.January.16.6
Effect of low temperatures on BAX and BCL2 proteins in rats with spinal cord ischemia reperfusion injury
Authors: P. Zhu, M.Y. Zhao, X.H. Li, Q. Fu, Z.F. Zhou, C.F. Huang, X.S. Zhang, H.L. Huang, Y. Tan, J.X. Li, J.N. Li, S. Huang, M. Ashraf, C. Lu, J.M. Chen, J. Zhuang and H.M. Guo
We evaluated changes in BAX and BCL2 expression levels after spinal cord ischemia/reperfusion injury (SCII) and hypothermia during operations in rats. Eighty rats were divided into four groups: Group A (N = 20, 18°C); Group B (N = 20, 28°C); Group C (N = 20, room temperature); and Group D (N = 20, sham operation control). Spinal cord ischemia was .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.10
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.10