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Biomarker

Human Genetics   Research Article

Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer

Authors: D.K. Sun, L. Wang, J.M. Wang and P. Zhang

Dickkopf-1 (DKK-1) is a secreted protein that inhibits Wnt signaling. However, the clinical significance and prognostic value of serum DKK-1 levels have not been previously investigated in bladder cancer in Chinese patients. Blood samples were taken from 94 consecutive patients diagnosed with bladder cancer and 60 healthy control subjects. Serum DKK-1 exp.. Read More»

Genet. Mol. Res. 14(4):
2015.December.23.5
DOI:
10.4238/2015.December.23.5
Human Genetics   Research Article

Circulating miR-125b as a biomarker of Ewing�s sarcoma in Chinese children

Authors: C.L. Nie, W.H. Ren, Y. Ma, J.S. Xi and B. Han

Previous studies indicated that microRNA-125b (miR-125b) has an important role in the progression of Ewing’s sarcoma (ES). The purpose of the current study was to examine expression changes of miR-125b in the serum of ES patients and evaluate if the expression level of miR-125b could serve as a new biomarker for ES. This study was performed on patie.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.12
DOI:
10.4238/2015.December.29.12