Bladder Cancer
Expression analysis of OIP5-AS1 in bladder tissues
Authors: Feraydoon Abdolmaleki, Soudeh Ghafoui-Fard, Mohammad Taheri, Alireza Mordadi, Mandana Afasharpad, Abolghasem Nikfallah, Bashir Nazparvar, Vahid Kholghi Oskooei, Mir Davood Omrani
Long non-coding RNAs (lncRNAs) have crucial roles in regulation of many aspects of cell functions which are related with carcinogenesis process. The lncRNA Opa Interacting Protein 5-antisense 1 (OIP5-AS1) is among lncRNAs whose roles in some human malignancies have been elucidated. In the current study, we aimed at identification of the role of this lncRN.. Read More»
- Genet. Mol. Res. 18(1):
Expression profiles of variation integration genes in bladder urothelial carcinoma
Authors: J.M. Wang, Y.Q. Wang, Z.L. Gao, J.T. Wu, B.K. Shi and C.C. Yu
Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.9
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.9
Parallel proteomic analysis in muscle-invasive bladder transitional cell carcinoma and cancer-related stroma
Authors: H.T. Niu, X.J. Qi, Y.Q. Liu, Y.W. Cao, Q. Dong and X.S. Wang
To bring about improvements in cancer biology research and elucidate mechanism-based therapeutic targets, we studied the proteome expression profile of purified normal urothelial cells (cancer cells) and normal stromal cells (cancerous stromal cells). Based on the expression profile, biomarker discovery and the mechanisms of multi-step carcinogenesis were.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.28
- DOI:
- 10.4238/2013.February.28.28
Association between MYC rs9642880[T] allele and bladder cancer risk: a meta-analysis
Authors: Y. Zhao, J.G. Qi, N. Yang, Y.L. Lin, J. Liang and X. Zhu
A single nucleotide polymorphism of MYC rs9642880 (G>T) at the 8q24.1 locus is thought to be associated with bladder cancer risk based on the results of genome-wide association studies, but the results remain inconclusive. To assess the association between rs9642880[T] allele and bladder cancer risk, we performed this meta-analysis including 18 case-co.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.39
- DOI:
- 10.4238/2015.November.18.39
729G/C polymorphism in Toll-like receptor 4 results in increased susceptibility to bladder cancer
Authors: B. Wan, J. Tan, Q. Zeng, L.Y. He, Y. Gan, Y.B. Dai and K. Yao
In this study, the association between the 729G/C polymorphism in Toll-like receptor 4 (TLR4) and the risk of bladder cancer was investigated. A total of 376 patients with bladder cancer and 380 healthy volunteers from the Third Xiangya Hospital of Central South University (China) were enrolled in this study between January 20.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.30.26
- DOI:
- 10.4238/2015.November.30.26
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder cancer risk
Authors: D.Y. Zhong H.Y. Chu M.L. Wang L. Ma D.N. Shi Z.D. Zhang
The functional polymorphism Ser326Cys (rs1052133) in the human 8-oxoguanine DNA glycosylase (hOGG1) gene has been implicated in bladder cancer risk. However, reports of this association between the Ser326Cys polymorphism and bladder cancer risk are conflicting. In order to help clarify this relationship, we made a meta-analysis of seven case-control studi.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.26.4
- DOI:
- 10.4238/2012.September.26.4
Correlation of aberrant expression of p53, Rad50, and cyclin-E proteins with microsatellite instability in gallbladder adenocarcinomas
Authors: P.K. Mishra, S.K. Jatawa, G.V. Raghuram, N. Pathak, A. Jain,A. Tiwari, S. Varshney and K.K. Maudar
Gallbladder carcinoma is an uncommon, but highly malignant tumor, with poor prognostic, and diagnostic manifestations in early stages. The Indian Council of Medical Research reported increased incidence of gallbladder carcinoma in the surviving population of the Bhopal gas tragedy that involved exposure of more than 500,000 pe.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr653
- DOI:
- 10.4238/vol8-4gmr653
Prognostic role of microRNA-100 in patients with bladder cancer
Authors: Y.H. Cao, H.H. Zhang,H.F. Xu, Y.J. Duan, Q. Li, B. Huang
We investigated the clinical significance and prognostic value of microRNA-100 (miR-100) in bladder cancer. Quantitative real-time polymerase chain reaction was used to analyze the expression of miR-100 in 92 pairs of human bladder cancer and adjacent normal tissue samples. Overall survival (OS) curves were plotted using the K.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.6
- DOI:
- 10.4238/2015.December.7.6
Vitamin D receptor genetic variants are associated with susceptibility of gallbladder adenocarcinoma in a Chinese cohort
Authors: Z. Li, W.T. Yuan, S.J. Ning and S.J. Zhang
The aim of this study was to test for the possible association between vitamin D receptor (VDR) genetic variants and susceptibility to gallbladder cancer (GBC). A total of 291 GBC cases were recruited and 396 gender- and age-matched healthy volunteers were enrolled as controls. The VDR gene polymorphisms were determined in all.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.18
- DOI:
- 10.4238/2014.July.24.18
Association between B7-H1 expression and bladder cancer: a meta-analysis
Authors: Y.U. Wang, A.N.G. Liu and S.H.A.N. Zhao
B7 homolog 1 (B7-H1), which is also known as programmed death-L1, is an important member of the B7/CD28 costimulatory factor superfamily, which are emerging as important mediators of various host immune responses. B7-H1 is differentially expressed in various cell subsets and to different extents in human and murine cells. Human B7-H1 is constitutively exp.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.6
- DOI:
- 10.4238/2015.February.13.6