Bladder Cancer
Clinical significance of fibroblast growth factor receptor-3 mutations in bladder cancer: a systematic review and meta-analysis..
Authors: X. Liu, W. Zhang, D. Geng, J. He, Y. Zhao and L. Yu
Mutations in the fibroblast growth factor receptor-3 (FGFR3) gene are frequently found in bladder cancer, but their prognostic value remains controversial. To globally summarize the association between FGFR3 mutations and the grade and stage of bladder cancer, and to analyze the predictive role of FGFR3 mutations with respect .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.20.12
- DOI:
- 10.4238/2014.February.20.12
Clinical significance of fibroblast growth factor receptor-3 mutations in bladder cancer: a systematic review and meta-analysis
Authors: X. Liu, W. Zhang, D. Geng, J. He, Y. Zhao and L. Yu
Mutations in the fibroblast growth factor receptor-3 (FGFR3) gene are frequently found in bladder cancer, but their prognostic value remains controversial. To globally summarize the association between FGFR3 mutations and the grade and stage of bladder cancer, and to analyze the predictive role of FGFR3 mutations with respect .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.20.12
- DOI:
- http://dx.doi.org/10.4238/2014.February.20.12
Prostate stem cell antigen rs2294008 (C>T) polymorphism and bladder cancer risk: a meta-analysis based on cases and controls
Authors: Y. Zhao, Z.L. Gui, S. Liao, F. Gao, Y.Z. Ge and R.P. Jia
Several published articles have evaluated the association between the prostate stem cell antigen (PSCA) rs2294008 (C>T) polymorphism and bladder cancer risk, but the results remain inconclusive. In order to derive a more precise estimation of the association, we performed a meta-analysis of four case-control studies that in.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.7
- DOI:
- 10.4238/2014.July.25.7
Meta-analysis of epidemiological studies of association of P53 codon 72 polymorphism with bladder cancer
Authors: D.B. Li, X. Wei, L.H. Jiang, Y. Wang and F. Xu
Although there have been many studies investigating a possible association between p53 codon 72 polymorphism and risk of bladder cancer, the results have been inconsistent. We conducted a meta-analysis of six epidemiological studies, which included 597 bladder cancer cases and 731 controls. Patients with bladder cancer had a s.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr882
- DOI:
- 10.4238/vol9-3gmr882
CCR2-64I is a risk factor for development of bladder cancer
Authors: K.F. Narter, B. Agachan, S. Sozen, Z.B. Cincin and T. Isbir
Chemokines are potent proinflammatory cytokines that are implicated in numerous inflammatory diseases. Proinflammatory gene polymorphisms lead to variations in the production and concentration of inflammatory proteins. We investigated a possible association between polymorphisms in chemokine and chemokine receptor genes (MCP-1.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr829
- DOI:
- 10.4238/vol9-2gmr829
Upregulation of miR-3658 in bladder cancer and tumor progression
Authors: Y.J. Chen, H.F. Wang, M. Liang, R.C. Zou, Z.R. Tang and J.S. Wang
Despite increasing advances in surgical techniques and adjuvant chemotherapies, bladder cancer remains the ninth leading cause of male malignancy-associated deaths worldwide. Several microRNAs (miRNAs) have been identified to be closely associated with the progression and prognosis of, and response to treatments in various hum.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049048
- DOI:
- 10.4238/gmr15049048
Loss of STAG2 causes aneuploidy in normal human bladder cells
Authors: X. Li, T.W. Zhang, J.L. Tang, P.P. Fa, J.X. Lu, F.M. Qi, Z.M. Cai, C.X. Liu and X.J. Sun
The aim of this study was to determine how the function of human stromal antigen 2 (STAG2) plays an important role in proper chromosome separation. STAG2 mRNA in normal bladder cells and bladder tumor cells was evaluated by RT-PCR. The protein levels of STAG2 in normal bladder cells and bladder tumor cells were determined by western blot. A cell prolifera.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.24
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.24
CYP1A2-163C/A (rs762551) polymorphism and bladder cancer risk: a case-control study
Authors: Y.L. Song, L. Wang, J.C. Ren and Z.H. Xu
To date, no study has investigated the association between CYP1A2-163C/A polymorphism and bladder cancer risk in a Chinese population. Here, we extracted genomic DNA from peripheral white blood cells, and differentiated CYP1A2 alleles by polymerase chain reaction-based restriction fragment length polymorphism methods. Differen.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026298
- DOI:
- 10.4238/gmr.15026298
Gene expression study related with the intrinsic pathway of apoptosis in bladder cancer by real-time PCR technique
Authors: D.F. Barione, F.S.N. Lizarte, P.C. Novais, C.A.M. de Carvalho, F.C.B. Valeri, F.M. Peria, H.F. de Oliveira, D.L. Zanette, W.A. Silva Jr., A.J. Cologna, R.B. Reis, S. Tucci Jr., A.C.P. Martins, D.P.C. Tirapelli and L.F. Tirapelli
We examined the expression of anti-apoptotic genes (XIAP and Bcl-2) and apoptotic genes (cytochrome c, caspase-9, Apaf-1) in tissue samples of patients with superficial bladder cancer. Thirty-two bladder cancer tissue samples (8 papillary urothelial neoplasm of low malignant potential, 10 low-grade, and 14 high-grade) and 8 normal bladder tissue samples f.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.4
- DOI:
- 10.4238/2013.April.2.4
Correlation of tumor relapse and elevated expression of survivin and vascular endothelial growth factor in superficial bladder transitional cell carcinoma
Authors: Y.W. Sun, Q. Xuan, Q.A. Shu, S.S. Wu, H. Chen, J. Xiao, P. Xiang, Y.P. Zhu, F.L. Wang and S.T. Zhao
Survivin and vascular endothelial growth factor (VEGF) are newly discovered tumor markers closely correlated with bladder cancer. We analyzed the expression of survivin and VEGF in paraffin-embedded tumor tissues from 78 patients with bladder transitional cell carcinoma (BTCC) using an immunohistochemistry method. Normal bladder mucosae from 10 non-BTCC c.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.21
- DOI:
- 10.4238/2013.April.2.21