Bladder Cancer
ERCC1 C118T polymorphism has predictive value for platinum-based chemotherapy in patients with late-stage bladder cancer
Authors: Z.C. Xu, H.Z. Cai, X. Li, W.Z. Xu, T. Xu, B. Yu, Q. Zou and L. Xu
This study aims to investigate the association between ERCC1 codon C118T polymorphism and the response rate of platinum-based chemotherapy in patients with late-stage bladder cancer. A total of 41 eligible patients histologically confirmed as having stage IV muscle-invasive transitional cell carcinoma of the bladder were treat.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027801
- DOI:
- 10.4238/gmr.15027801
Gene expression profile and enrichment pathways in different stages of bladder cancer
Authors: Z.-Q. Fang, W.-D. Zang, R. Chen, B.-W. Ye, X.-W. Wang, S.-H. Yi, W. Chen, F. He and G. Ye
Bladder cancer is a highly heterogeneous neoplasm. We examined the gene expression profile in 3 bladder cancer stages (Ta, T1, T2) using expression microarray analysis of 40 bladder tumors. Differentially expressed genes were found by the t-test, with <0.005 as the significance threshold. KEGG pathway-enrichment analysis was used to study the signaling.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.6.1
- DOI:
- 10.4238/2013.May.6.1
Meta-analysis of the relationship between slow acetylation of N-acetyl transferase 2 and the risk of bladder cancer
Authors: Y. An , H. Li, K.J. Wang, X.H. Liu, M.X. Qiu, Y. Liao, J.L. Huang and X.S. Wang
The incidence of bladder cancer is closely associated with exposure to aromatic amines, that can cause cancer only after metabolic activation regulated by N-acetyl transferase 1 and 2 (NAT1 and NAT2). Many studies have indicated that slow acetylation of NAT2 increases the risk of bladder cancer. The major risk factor is tobacco smoke; however, some studie.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.14.17
- DOI:
- 10.4238/2015.December.14.17
CYFRA21-1 levels could be a biomarker for bladder cancer: a meta-analysis
Authors: L.I. Kuang,W.J. Song,H.M. Qing,S. Yan and F.L. Song
The proteolytic region of cytokeratin-19, referred to as CYFRA21-1, is a soluble molecule present in the serum and other body fluids, and is considered a tumor marker in several neoplastic diseases. To examine whether urinary or serum samples containing CYFRA21-1 can be used as biomarkers for bladder cancer, we conducted a comprehensive meta-analysis of 3.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.6
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.6
Chemokine receptor CXCR4 and its ligand CXCL12 expressions and clinical significance in bladder cancer
Authors: D.L. Yang, M.M. Xin, J.S. Wang, H.Y. Xu, Q. Huo, Z.R. Tang and H.F. Wang
It is well known that chemokine receptors and their ligands play important roles in mediating the invasion and metastasis of malignant tumors. This aim of this study was to investigate the expression and clinical significance of chemokine receptor CXCR4 and its ligand CXCL12 in bladder tumor tissues. Cancerous and adjacent normal bladder tissues were coll.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.43
- DOI:
- 10.4238/2015.December.21.43
Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer
Authors: D.K. Sun, L. Wang, J.M. Wang and P. Zhang
Dickkopf-1 (DKK-1) is a secreted protein that inhibits Wnt signaling. However, the clinical significance and prognostic value of serum DKK-1 levels have not been previously investigated in bladder cancer in Chinese patients. Blood samples were taken from 94 consecutive patients diagnosed with bladder cancer and 60 healthy control subjects. Serum DKK-1 exp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.5
- DOI:
- 10.4238/2015.December.23.5