Breast Cancer
Roles of microRNA-221/222 in type 2 diabetic patients with post-menopausal breast cancer
Authors: M.Y. Li, S.R. Pan and A.Y. Qiu
The aim of the research was to examine the expression level of microRNA221/222 (miR-221/222) in the serum of patients with type 2 diabetes mellitus (T2DM) who are also diagnosed with post-menopausal breast cancer. We aimed to evaluate the differences in microRNA expression in patients with T2DM alone, patients with post-menopa.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027259
- DOI:
- 10.4238/gmr.15027259
Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer
Authors: X. Wang and Z.H. Huang
The current study aimed at evaluating the association between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.7
- DOI:
- 10.4238/2015.August.28.7
Androgen receptor (CAG)n polymorphisms and breast cancer risk in a Han Chinese population
Authors: J. Dang, L. Peng, H.J. Zhong and Z.H. Huo
The androgen receptor (AR) is involved in the differentiation and growth of breast cancer. Genetic markers in the AR gene have a plausible role in modulating the risk of breast cancer. In this study, we studied the association of breast cancer and the trinucleotide repeat polymorphism (CAG)n in exon 1 of the AR gene in 202 patients with breast cancer and .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.10
- DOI:
- 10.4238/2015.August.28.10
Molecular-level effects of eribulin and paclitaxel on breast cancer based on differential co-expression network analysis
Authors: J. Qin and Y.H. Chen
We investigated the effects of eribulin and paclitaxel on breast cancer (BC) by exploring molecular biomarkers and pathways. Co-expression networks were constructed by differentially co-expressed genes and links, and centralities were analyzed to explore the hub genes. Pathway-enrichment analysis was performed. The hub genes w.. Read More»
- Genet. Mol. Res. 15(2):
Direct preparation protocol to obtain mitotic chromosomes from canine mammary tumors
Authors: C.S.D. Morais, P.R.A.M. Affonso, J.A. Bitencourt and A.A. Wenceslau
Currently, mammary neoplasms in female canines are a serious problem in veterinary clinics. In addition, the canine species is an excellent disease model for human oncology because of the biological and genetic similarities between the species. Cytogenetics has allowed further study of the characterization of neoplasms in canines. We hypothesized that the.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.49
- DOI:
- 10.4238/2015.December.29.49